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Athanassios Kakkanas

Explore the profile of Athanassios Kakkanas including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 66
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Recent Articles
1.
Moustafa S, Kassela K, Bampali M, Dovrolis N, Kakkanas A, Beloukas A, et al.
Viruses . 2022 Nov; 14(11). PMID: 36423130
Hepatitis C virus (HCV) core protein is a multifunctional protein that is involved in the proliferation, inflammation, and apoptosis mechanism of hepatocytes. HCV core protein genetic variability has been implicated...
2.
Kakkanas A, Karamichali E, Koufogeorgou E, Kotsakis S, Georgopoulou U, Foka P
Biomolecules . 2022 Aug; 12(8). PMID: 36008946
The emerging SARS-CoV and SARS-CoV-2 belong to the family of "common cold" RNA coronaviruses, and they are responsible for the 2003 epidemic and the current pandemic with over 6.3 M...
3.
Karamichali E, Chihab H, Kakkanas A, Marchio A, Karamitros T, Pogka V, et al.
Front Microbiol . 2018 Dec; 9:2942. PMID: 30559733
Defective interfering (DI) RNAs have been detected in several human viruses. HCV in-frame deletions mutants (IFDMs), missing mainly the envelope proteins, have been found in patient sera and liver tissues....
4.
Karamichali E, Serti E, Gianneli A, Papaefthymiou A, Kakkanas A, Foka P, et al.
Infect Genet Evol . 2017 Jul; 54:251-262. PMID: 28687362
Hepatitis C virus (HCV) is an RNA positive strand virus, member of the Flaviviridae family. The HCV viral particle is composed of a capsid containing the genome, surrounded by an...
5.
Foka P, Karamichali E, Dalagiorgou G, Serti E, Doumba P, Pissas G, et al.
J Hepatol . 2013 Aug; 60(1):30-8. PMID: 23978712
Background & Aims: HCV relies on host lipid metabolism to complete its life cycle and HCV core is crucial to this interaction. Liver secreted ANGPTL-3 is an LXR- and HNF-1α-regulated...
6.
Kotta-Loizou I, Vassilaki N, Pissas G, Kakkanas A, Bakiri L, Bartenschlager R, et al.
J Gen Virol . 2013 Apr; 94(Pt 7):1528-1534. PMID: 23580428
Chronic viral hepatitis C is characterized by iron accumulation in the liver, and hepcidin regulates iron absorption. Hepatitis C virus (HCV) core+1/ARFP is a novel protein produced by a second...
7.
Budkowska A, Kakkanas A, Nerrienet E, Kalinina O, Maillard P, Horm S, et al.
PLoS One . 2011 Feb; 6(1):e15871. PMID: 21283512
The biological role of the protein encoded by the alternative open reading frame (core+1/ARF) of the Hepatitis C virus (HCV) genome remains elusive, as does the significance of the production...
8.
Boumlic A, Vassilaki N, Dalagiorgou G, Kochlios E, Kakkanas A, Georgopoulou U, et al.
Virus Res . 2010 Oct; 155(1):213-20. PMID: 20959129
The hepatitis C virus possesses an alternative open reading frame overlapping the Core gene, whose products are referred to as Core+1 or alternative reading frame (ARF) or F protein(s). Extensive...