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Ulrike Ruch

Explore the profile of Ulrike Ruch including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 235
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Recent Articles
1.
Steinhoff G, Nesteruk J, Wolfien M, Grosse J, Ruch U, Vasudevan P, et al.
Adv Drug Deliv Rev . 2017 Oct; 120:2-24. PMID: 29054357
After two decades of intensive research and attempts of clinical translation, stem cell based therapies for cardiac diseases are not getting closer to clinical success. This review tries to unravel...
2.
Steinhoff G, Nesteruk J, Wolfien M, Kundt G, Borgermann J, David R, et al.
EBioMedicine . 2017 Aug; 22:208-224. PMID: 28781130
Objective: The phase III clinical trial PERFECT was designed to assess clinical safety and efficacy of intramyocardial CD133 bone marrow stem cell treatment combined with CABG for induction of cardiac...
3.
Skorska A, Muller P, Gaebel R, Grosse J, Lemcke H, Lux C, et al.
Stem Cell Res Ther . 2017 Feb; 8(1):33. PMID: 28187777
Background: CD133 stem cells represent a promising subpopulation for innovative cell-based therapies in cardiovascular regeneration. Several clinical trials have shown remarkable beneficial effects following their intramyocardial transplantation. Yet, the purification...
4.
Prinz B, Harvey K, Wilcke L, Ruch U, Engelberg K, Biller L, et al.
Sci Rep . 2016 Oct; 6:34479. PMID: 27698395
Central to the pathogenesis of malaria is the proliferation of Plasmodium falciparum parasites within human erythrocytes. Parasites invade erythrocytes via a coordinated sequence of receptor-ligand interactions between the parasite and...
5.
Tomlins A, Ben-Rached F, Williams R, Proto W, Coppens I, Ruch U, et al.
Autophagy . 2013 Sep; 9(10):1540-52. PMID: 24025672
Amino acid utilization is important for the growth of the erythrocytic stages of the human malaria parasite Plasmodium falciparum, however the molecular mechanism that permits survival of the parasite during...
6.
Kono M, Herrmann S, Loughran N, Cabrera A, Engelberg K, Lehmann C, et al.
Mol Biol Evol . 2012 Mar; 29(9):2113-32. PMID: 22389454
The inner membrane complex (IMC) is a unifying morphological feature of all alveolate organisms. It consists of flattened vesicles underlying the plasma membrane and is interconnected with the cytoskeleton. Depending...
7.
Haase S, Herrmann S, Gruring C, Heiber A, Jansen P, Langer C, et al.
Mol Microbiol . 2009 Jan; 71(4):1003-17. PMID: 19170882
A short motif termed Plasmodium export element (PEXEL) or vacuolar targeting signal (VTS) characterizes Plasmodium proteins exported into the host cell. These proteins mediate host cell modifications essential for parasite...