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Gustav Steinhoff

Explore the profile of Gustav Steinhoff including associated specialties, affiliations and a list of published articles. Areas
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Articles 161
Citations 2808
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Recent Articles
1.
Vasudevan P, Wolfien M, Lemcke H, Lang C, Skorska A, Gaebel R, et al.
Genome Med . 2023 Aug; 15(1):61. PMID: 37563727
Background: The immune response is a crucial factor for mediating the benefit of cardiac cell therapies. Our previous research showed that cardiomyocyte transplantation alters the cardiac immune response and, when...
2.
Ahmad B, Skorska A, Wolfien M, Sadraddin H, Lemcke H, Vasudevan P, et al.
Int J Mol Sci . 2022 Aug; 23(16). PMID: 36012110
Ventricular arrhythmias associated with myocardial infarction (MI) have a significant impact on mortality in patients following heart attack. Therefore, targeted reduction of arrhythmia represents a therapeutic approach for the prevention...
3.
Salybekov A, Wolfien M, Kobayashi S, Steinhoff G, Asahara T
Cells . 2021 Dec; 10(12). PMID: 34943774
Stem/progenitor cell transplantation is a potential novel therapeutic strategy to induce angiogenesis in ischemic tissue, which can prevent major amputation in patients with advanced peripheral artery disease (PAD). Thus, clinicians...
4.
Lang C, Vasudevan P, Doring P, Gabel R, Lemcke H, Lindner T, et al.
Sci Rep . 2021 Jun; 11(1):11625. PMID: 34079005
Novel therapeutic strategies aiming at improving the healing process after an acute myocardial infarction are currently under intense investigation. The mouse model plays a central role for deciphering the underlying...
5.
Steinhoff G
Cells . 2021 Apr; 10(3). PMID: 33800252
The development of stem-cell-based and regenerative therapies for cardiovascular and other diseases has faced an unexpected roadblock in clinical translation [...].
6.
Vasudevan P, Wolfien M, Lemcke H, Lang C, Skorska A, Gaebel R, et al.
Cells . 2020 Aug; 9(8). PMID: 32756334
We investigated the influence of syngeneic cardiomyocyte transplantation after myocardial infarction (MI) on the immune response and cardiac function. Methods and Results: We show for the first time that the...
7.
Wolfien M, Klatt D, Salybekov A, Ii M, Komatsu-Horii M, Gaebel R, et al.
EBioMedicine . 2020 Jul; 57:102862. PMID: 32629392
Background: Bone marrow stem cell clonal dysfunction by somatic mutation is suspected to affect post-infarction myocardial regeneration after coronary bypass surgery (CABG). Methods: Transcriptome and variant expression analysis was studied...
8.
Zarniko N, Skorska A, Steinhoff G, David R, Gaebel R
Biomedicines . 2020 Jun; 8(6). PMID: 32545336
Several cell populations derived from bone marrow (BM) have been shown to possess cardiac regenerative potential. Among these are freshly isolated CD133 hematopoietic as well as culture-expanded mesenchymal stem cells....
9.
Lang C, Doring P, Gabel R, Vasudevan P, Lemcke H, Muller P, et al.
Cells . 2020 Jun; 9(6). PMID: 32486211
Angiogenesis plays a central role in the healing process following acute myocardial infarction. The PET tracer [Ga]-NODAGA-RGD, which is a ligand for the αβ integrin, has been investigated for imaging...
10.
Muller-Ruch U, Skorska A, Lemcke H, Steinhoff G, David R
Adv Drug Deliv Rev . 2020 Apr; 165-166:96-104. PMID: 32305352
In biomedical research, enormous progress is being made and new candidates for putative medicinal products emerge. However, most published preclinical data are not conducted according to the standard Good Laboratory...