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» Authors » Ulrich Pachmann

Ulrich Pachmann

Explore the profile of Ulrich Pachmann including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 325
Followers 0
Related Specialties
Oncology
General Medicine
Biochemistry
Top 10 Co-Authors
Katharina Pachmann
Monika Pizon
Dorothea Sonja Schott
Dorothea Schott
Klaus Hoffken
Walter Sibrowski
Marc Hoemberg
Uwe Cassens
Torsten Kroll
Oumar Camara
Published In
Clin Chem Lab Med
Oncotarget
World J Surg Oncol
Eur J Haematol
J Clin Oncol
Affiliations
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Recent Articles
1.
Chick Chorioallantoic Membrane (CAM) Assays as a Model of Patient-Derived Xenografts from Circulating Cancer Stem Cells (cCSCs) in Breast Cancer Patients
Pizon M, Schott D, Pachmann U, Schobert R, Pizon M, Wozniak M, et al.
Cancers (Basel) . 2022 Mar; 14(6). PMID: 35326627
Background: cCSCs are a small subset of circulating tumor cells with cancer stem cell features: resistance to cancer treatments and the capacity for generating metastases. PDX are an appreciated tool...
2.
Influence of adjuvant radiotherapy on circulating epithelial tumor cells and circulating cancer stem cells in primary non-metastatic breast cancer
Schott D, Pizon M, Pachmann U, Pachmann K, Schobert R, Wittig A, et al.
Transl Oncol . 2021 Jan; 14(3):101009. PMID: 33453469
Background: There is an unmet need to identify biomarkers that directly reflect response to adjuvant radiotherapy (RT). Circulating epithelial tumor cells (CETCs) represent the liquid component of solid tumors and...
3.
Influence of endocrine therapy on the ratio of androgen receptor (AR) to estrogen receptor (ER) positive circulating epithelial tumor cells (CETCs) in breast cancer
Pizon M, Lux D, Pachmann U, Pachmann K, Schott D
J Transl Med . 2018 Dec; 16(1):356. PMID: 30547831
Background: The androgen receptor (AR) is expressed in the majority of breast cancers and across the main breast cancer subtypes. Despite the high frequency of AR expression in breast cancer...
4.
B7-H3 on circulating epithelial tumor cells correlates with the proliferation marker, Ki-67, and may be associated with the aggressiveness of tumors in breast cancer patients
Pizon M, Schott D, Pachmann U, Pachmann K
Int J Oncol . 2018 Sep; 53(5):2289-2299. PMID: 30226585
Circulating epithelial tumor cells (CETCs) in peripheral blood are a prerequisite for the development of metastases. B7-H3 is an important immune checkpoint member of the B7 family and inhibits T-cell...
5.
Sensitive detection of PD-L1 expression on circulating epithelial tumor cells (CETCs) could be a potential biomarker to select patients for treatment with PD-1/PD-L1 inhibitors in early and metastatic solid tumors
Schott D, Pizon M, Pachmann U, Pachmann K
Oncotarget . 2017 Oct; 8(42):72755-72772. PMID: 29069824
Background: The current cancer research strongly focuses on immune therapies, where the PD-1, with its ligands plays an important role. It is known that PD-L1 is frequently up-regulated in a...
6.
The number of tumorspheres cultured from peripheral blood is a predictor for presence of metastasis in patients with breast cancer
Pizon M, Schott D, Pachmann U, Pachmann K
Oncotarget . 2016 Jun; 7(30):48143-48154. PMID: 27340862
Background: Tumor metastases are the major cause of cancer morbidity and mortality. A subpopulation of tumor cells with stem-like properties is assumed to be responsible for tumor invasion, metastasis, heterogeneity...
7.
Insulin-like growth factor receptor I (IGF-IR) and vascular endothelial growth factor receptor 2 (VEGFR-2) are expressed on the circulating epithelial tumor cells of breast cancer patients
Pizon M, Zimon D, Pachmann U, Pachmann K
PLoS One . 2013 Feb; 8(2):e56836. PMID: 23418605
Background: Circulating epithelial tumor cell (CETC) analysis is a promising diagnostic field for estimating the risk for metastatic relapse and progression in patients with malignant disease. CETCs characterization can be...
8.
Demasking of epithelial cell adhesion molecule (EpCAM) on circulating epithelial tumor cells by Tween®20 treatment in breast cancer patients
Hekimian K, Stein E, Pachmann U, Pachmann K
Clin Chem Lab Med . 2012 Apr; 50(4):701-8. PMID: 22505561
Background: The epithelial cell adhesion molecule (EpCAM) embedded in the plasma membrane of circulating epithelial tumor cells (CETC) is used for detection and enrichment of circulating tumor cells in peripheral...
9.
Monitoring the response of circulating epithelial tumor cells to adjuvant chemotherapy in breast cancer allows detection of patients at risk of early relapse
Pachmann K, Camara O, Kavallaris A, Krauspe S, Malarski N, Gajda M, et al.
J Clin Oncol . 2008 Mar; 26(8):1208-15. PMID: 18323545
Purpose: To demonstrate that it is possible to monitor the response to adjuvant therapy by repeated analysis of circulating epithelial tumor cells (CETCs) and to detect patients early who are...
10.
An increase in cell number at completion of therapy may develop as an indicator of early relapse: quantification of circulating epithelial tumor cells (CETC) for monitoring of adjuvant therapy in breast cancer
Pachmann K, Dengler R, Lobodasch K, Frohlich F, Kroll T, Rengsberger M, et al.
J Cancer Res Clin Oncol . 2007 Jul; 134(1):59-65. PMID: 17611779
Purpose: Treatment efficiency of adjuvant therapy in breast cancer is only revealed after several years by statistical evaluation and gives no answer for the individual patient. We here present a...