Torsten Kroll
Overview
Explore the profile of Torsten Kroll including associated specialties, affiliations and a list of published articles.
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17
Citations
256
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Recent Articles
1.
Richter A, Morl H, Thielemann M, Kleemann M, Geissen R, Schwarz R, et al.
Nat Commun
. 2025 Jan;
16(1):540.
PMID: 39788971
Although sex determination is a fundamental process in vertebrate development, it is very plastic. Diverse genes became major sex determinants in teleost fishes. Deciphering how individual sex-determining genes orchestrate sex...
2.
Schuhwerk H, Kleemann J, Gupta P, van Roey R, Armstark I, Kreileder M, et al.
Cell Rep
. 2022 Dec;
41(11):111819.
PMID: 36516781
The DNA damage response (DDR) and epithelial-to-mesenchymal transition (EMT) are two crucial cellular programs in cancer biology. While the DDR orchestrates cell-cycle progression, DNA repair, and cell death, EMT promotes...
3.
Ahmad M, Kruger B, Kroll T, Vettorazzi S, Dorn A, Mengele F, et al.
Bone Res
. 2022 Apr;
10(1):33.
PMID: 35383146
Identification of regulators of osteoblastogenesis that can be pharmacologically targeted is a major goal in combating osteoporosis, a common disease of the elderly population. Here, unbiased kinome RNAi screening in...
4.
Guerra G, May D, Kroll T, Koch P, Groth M, Wang Z, et al.
Cells
. 2021 Dec;
10(12).
PMID: 34943873
SMG6 is an endonuclease, which cleaves mRNAs during nonsense-mediated mRNA decay (NMD), thereby regulating gene expression and controling mRNA quality. SMG6 has been shown as a differentiation license factor of...
5.
Ahmad M, Kroll T, Jakob J, Rauch A, Ploubidou A, Tuckermann J
Sci Rep
. 2018 Sep;
8(1):14045.
PMID: 30232406
Osteoblasts are responsible for the maintenance of bone homeostasis. Deregulation of their differentiation is etiologically linked to several bone disorders, making this process an important target for therapeutic intervention. Systemic...
6.
Connell M, Chen H, Jiang J, Kuan C, Fotovati A, Chu T, et al.
Elife
. 2017 Oct;
6.
PMID: 28994651
Oriented cell division is one mechanism progenitor cells use during development and to maintain tissue homeostasis. Common to most cell types is the asymmetric establishment and regulation of cortical NuMA-dynein...
7.
Schuhwerk H, Bruhn C, Siniuk K, Min W, Erener S, Grigaravicius P, et al.
Nucleic Acids Res
. 2017 Oct;
45(19):11174-11192.
PMID: 28977496
One of the fastest cellular responses to genotoxic stress is the formation of poly(ADP-ribose) polymers (PAR) by poly(ADP-ribose)polymerase 1 (PARP1, or ARTD1). PARP1 and its enzymatic product PAR regulate diverse...
8.
Li H, Kroll T, Moll J, Frappart L, Herrlich P, Heuer H, et al.
Stem Cell Reports
. 2017 Sep;
9(4):1071-1080.
PMID: 28943256
Misoriented division of neuroprogenitors, by loss-of-function studies of centrosome or spindle components, has been linked to the developmental brain defects microcephaly and lissencephaly. As these approaches also affect centrosome biogenesis,...
9.
Yonemura Y, Li X, Muller K, Kramer A, Atigbire P, Mentrup T, et al.
J Cell Sci
. 2016 Sep;
129(20):3868-3877.
PMID: 27587840
Export out of the endoplasmic reticulum (ER) involves the Sar1 and COPII machinery acting at ER exit sites (ERES). Whether and how cargo proteins are recruited upstream of Sar1 and...
10.
Li H, Frappart L, Moll J, Winkler A, Kroll T, Hamann J, et al.
Cancer Res
. 2016 Aug;
76(21):6382-6395.
PMID: 27543603
Hypofertility is a risk factor for the development of testicular germ cell tumors (TGCT), but the initiating event linking these pathologies is unknown. We hypothesized that excessive planar division of...