U Schonbeck
Overview
Explore the profile of U Schonbeck including associated specialties, affiliations and a list of published articles.
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33
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2333
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Recent Articles
1.
Horton D, Libby P, Schonbeck U
Ann N Y Acad Sci
. 2002 Jan;
947:329-36.
PMID: 11795284
Interstitial collagen constitutes the predominant structural component of the fibrous cap of atherosclerotic plaque. The balance between synthesis and degradation of this extracellular matrix protein probably determines plaque stability and...
2.
Schonbeck U, Libby P
Circ Res
. 2001 Dec;
89(12):1092-103.
PMID: 11739273
Today, multiple lines of evidence support the view of atherosclerosis as a chronic inflammatory disease and implicate components of the immune system in atherogenesis. Recent work has documented overexpression of...
3.
Schonbeck U, Varo N, Libby P, Buring J, Ridker P
Circulation
. 2001 Nov;
104(19):2266-8.
PMID: 11696462
Background: The immune-signaling dyad CD40/CD40L promotes atherogenesis, and patients with unstable angina have elevated plasma levels of soluble CD40L (sCD40L) and membrane-bound CD40L. It is unknown, however, whether elevations of...
4.
Herman M, Sukhova G, Libby P, Gerdes N, Tang N, Horton D, et al.
Circulation
. 2001 Oct;
104(16):1899-904.
PMID: 11602491
Background: Loss of interstitial collagen, particularly type I collagen, the major load-bearing molecule of atherosclerotic plaques, renders atheroma prone to rupture. Initiation of collagen breakdown requires interstitial collagenases, a matrix...
5.
6.
Herman M, Sukhova G, Kisiel W, Foster D, Kehry M, Libby P, et al.
J Clin Invest
. 2001 May;
107(9):1117-26.
PMID: 11342575
Degradation of ECM, particularly interstitial collagen, promotes plaque instability, rendering atheroma prone to rupture. Previous studies implicated matrix metalloproteinases (MMPs) in these processes, suggesting that dysregulated MMP activity, probably due...
7.
Schonbeck U, Libby P
Cell Mol Life Sci
. 2001 Mar;
58(1):4-43.
PMID: 11229815
Until recently, the expression and primary function of the cell surface receptor CD40 and its ligand CD154 were considered restricted to B and T lymphocytes, and their interactions required for...
8.
Marx N, Mackman N, Schonbeck U, Yilmaz N, Hombach V, Libby P, et al.
Circulation
. 2001 Feb;
103(2):213-9.
PMID: 11208679
Background: Tissue factor (TF), expressed on the surface of monocytes and macrophages in human atherosclerotic lesions, acts as the major procoagulant initiating thrombus formation in acute coronary syndromes. Peroxisome proliferator-activated...
9.
Libby P, Aikawa M, Schonbeck U
Biochim Biophys Acta
. 2000 Dec;
1529(1-3):299-309.
PMID: 11111097
No abstract available.
10.
Shimizu K, Schonbeck U, Mach F, Libby P, Mitchell R
J Immunol
. 2000 Sep;
165(6):3506-18.
PMID: 10975872
Although interruption of CD40-CD40L interactions via their respective mAbs yields prolonged allograft survival, the relative importance of CD40 or CD40L on donor or host cells remains unknown. Moreover, it is...