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U M Marzec

Explore the profile of U M Marzec including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 330
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Recent Articles
1.
Travis B, Marzec U, Leo H, Momin T, Sanders C, Hanson S, et al.
Ann Biomed Eng . 2001 Sep; 29(8):657-64. PMID: 11556722
The clinical histories of the Medtronic Parallel (MP) and St. Jude Medical (SJM) Standard valves suggest pivot geometry influences the thrombogenic characteristics of bileaflet prostheses. This work studied the effects...
2.
Travis B, Marzec U, Ellis J, Davoodi P, Momin T, Hanson S, et al.
J Heart Valve Dis . 2001 Apr; 10(2):228-38. PMID: 11297211
Background And Aim Of The Study: The recent clinical history and experimental studies of the Medtronic Parallel (MP) valve suggest that bileaflet valve leakage flow is a primary initiator of...
3.
Harker L, Roskos L, Marzec U, Carter R, CHERRY J, SUNDELL B, et al.
Blood . 2001 Feb; 95(8):2514-22. PMID: 10753829
The effects of thrombopoietic stimulation on megakaryocytopoiesis, platelet production, and platelet viability and function were examined in normal volunteers randomized to receive single bolus subcutaneous injections of 3 microg/kg pegylated...
4.
Harker L, Marzec U, Kelly A
Stem Cells . 2000 Sep; 16 Suppl 2:107-19. PMID: 11012183
Endogenous thrombopoietin (TPO) stimulates platelet production in nonhuman primates dose-dependentbyinducing megakaryocyte development from early marrow hematopoietic progenitors and subsequent proliferation and endoreduplication. Recombinant human TPO, nonpegylated or pegylated recombinant human...
5.
Musselman D, Marzec U, Manatunga A, Penna S, Reemsnyder A, Knight B, et al.
Arch Gen Psychiatry . 2000 Sep; 57(9):875-82. PMID: 10986551
Background: Alterations in platelet reactivity have been previously posited to underlie the increased vulnerability of patients with depression to ischemic heart disease (IHD). The present study sought to determine whether...
6.
Harker L, Marzec U, Kelly A, Chronos N, Sundell I, Hanson S, et al.
Circulation . 1998 Dec; 98(22):2461-9. PMID: 9832493
Background: A recent study showed that clopidogrel reduces thrombo-occlusive complications in patients with symptomatic atherosclerosis more effectively than aspirin. Methods And Results: The effects of clopidogrel and aspirin have been...
7.
Harker L, Marzec U, Novembre F, Sundell I, Waller E, Karpatkin S, et al.
Blood . 1998 Jun; 91(12):4427-33. PMID: 9616135
Three chimpanzees experimentally infected with human immunodeficiency virus (HIV) developed significant chronic thrombocytopenia after 5, 4, and 2 years, with peripheral platelet counts averaging 64 +/- 19 x 10(3)/microL (P...
8.
Cole J, Marzec U, Gunthel C, Karpatkin S, Worford L, Sundell I, et al.
Blood . 1998 May; 91(9):3239-46. PMID: 9558379
Thrombocytopenia has been characterized in six patients infected with human immunodeficiency virus (HIV) with respect to the delivery of viable platelets into the peripheral circulation (peripheral platelet mass turnover), marrow...
9.
Sundell I, Marzec U, Kelly A, Chronos N, Petersen L, Hanson S, et al.
Circulation . 1997 Aug; 96(3):941-8. PMID: 9264505
Background: To enhance thrombolytic responses without increasing hemorrhagic risks, the antithrombotic effects of recombinant Lys-plasminogen (r-LysPgn), a prothrombolytic plasminogen intermediate, were examined in baboon models of thrombus formation and dissolution....
10.
Harker L, Marzec U, Kelly A, Cheung E, Tomer A, Nichol J, et al.
Blood . 1997 Jan; 89(1):155-65. PMID: 8978288
This report examines the effects on hematopoietic regeneration of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) (2.5 micrograms/ kg/d) alone and in combination with recombinant human granulocyte colony...