R B Stead
Overview
Explore the profile of R B Stead including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
140
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0
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Recent Articles
1.
Farese A, Cohen M, Stead R, Jackson 3rd W, MacVittie T
Radiat Res
. 2012 Sep;
178(5):403-13.
PMID: 22991919
Conventional daily administration of filgrastim is effective in reducing the duration of severe neutropenia and enhancing survival following lethal radiation, myelosuppressive cytotoxic therapy or myeloablation and stem cell transplantation. A...
2.
Farese A, Yang B, Roskos L, Stead R, MacVittie T
Bone Marrow Transplant
. 2003 Aug;
32(4):399-404.
PMID: 12900776
Daily administration of filgrastim decreases the duration of severe neutropenia in the clinical setting. A sustained-duration form of filgrastim, pegfilgrastim, significantly reduces scheduling protocols to a single injection per chemotherapy...
3.
Harker L, Marzec U, Novembre F, Sundell I, Waller E, Karpatkin S, et al.
Blood
. 1998 Jun;
91(12):4427-33.
PMID: 9616135
Three chimpanzees experimentally infected with human immunodeficiency virus (HIV) developed significant chronic thrombocytopenia after 5, 4, and 2 years, with peripheral platelet counts averaging 64 +/- 19 x 10(3)/microL (P...
4.
Harker L, Marzec U, Kelly A, Cheung E, Tomer A, Nichol J, et al.
Blood
. 1997 Jan;
89(1):155-65.
PMID: 8978288
This report examines the effects on hematopoietic regeneration of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) (2.5 micrograms/ kg/d) alone and in combination with recombinant human granulocyte colony...
5.
Harker L, Marzec U, Hunt P, Kelly A, Tomer A, Cheung E, et al.
Blood
. 1996 Jul;
88(2):511-21.
PMID: 8695799
Thrombopoietin (TPO) is the physiologic Mpl-ligand regulating platelet production. Pegylated human recombinant megakaryocyte growth and development factor (PEG-rHuMGDF), a truncated polypeptide Mpl-ligand derivitized with poly-(ethylene glycol), induces megakaryocyte endoreduplication and...
6.
Stead R, Harker L
Curr Opin Hematol
. 1996 May;
3(3):197-202.
PMID: 9372076
The cloning of the gene for the endogenous c-mpl ligand, also known as thrombopoietin, was first reported less than 2 years ago. Recombinant mpl ligands based on this gene have...
7.
Harker L, Hunt P, Marzec U, Kelly A, Tomer A, Hanson S, et al.
Blood
. 1996 Mar;
87(5):1833-44.
PMID: 8634430
The primary physiologic regulator of platelet production, Mpl ligand, has recently been cloned and characterized. To define the regulatory role of Mpl ligand on platelet production and function we measured...
8.
Anderson K, Goeger D, Carson R, Lee S, Stead R
N Engl J Med
. 1990 Feb;
322(5):315-7.
PMID: 2104958
No abstract available.
9.
Schuening F, Storb R, Stead R, GOEHLE S, Nash R, Miller A
Blood
. 1989 Jul;
74(1):152-5.
PMID: 2752107
Amphotropic helper-free retroviral vectors containing either the bacterial neomycin phosphotransferase gene (NEO) or a mutant dihydrofolate reductase gene (DHFR*) were used to infect canine hematopoietic progenitor cells. In previous experiments,...
10.
Stead R, Kwok W, Storb R, Miller A
Blood
. 1988 Mar;
71(3):742-7.
PMID: 3278755
Successful retroviral gene transfer into murine hematopoietic stem cells indicates the potential for somatic gene therapy in the treatment of certain human hereditary diseases. We developed a canine model to...