U Flatow
Overview
Explore the profile of U Flatow including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
335
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Recent Articles
1.
Ferguson A, Flatow U, Macdonald N, Larminat F, Bohr V, Steeg P
Cancer Res
. 1996 Jul;
56(13):2931-5.
PMID: 8674043
We report a functional link between expression of the metastasis suppressor gene nm23 and cancer cell sensitivity to the alkylating agent cisplatin. Cisplatin was 2-15-fold more inhibitory to the growth...
2.
Analysis of the spacer DNA between the cyclic AMP receptor protein binding site and the lac promoter
Flatow U, Rajendrakumar G, Garges S
J Bacteriol
. 1996 Apr;
178(8):2436-9.
PMID: 8636052
The role of the spacer region DNA between the cyclic AMP receptor protein (CRP) site and the RNA polymerase in the lac promoter was examined. We wanted to determine whether...
3.
Leone A, Flatow U, Vanhoutte K, Steeg P
Oncogene
. 1993 Sep;
8(9):2325-33.
PMID: 8395676
We report the phenotypic effects of transfection of human nm23-H1 cDNA into the human MDA-MB-435 breast carcinoma cell line. Upon mammary fat pad or subcutaneous injection into nude mice, both...
4.
Steeg P, De la Rosa A, Flatow U, Macdonald N, Benedict M, Leone A
Breast Cancer Res Treat
. 1993 Jan;
25(2):175-87.
PMID: 8347849
The majority of breast cancer patients succumb to metastatic disease. We summarize published and recent research concerning the nm23 gene in breast cancer metastasis. In a murine developmental study, nm23...
5.
Leone A, Flatow U, King C, Sandeen M, Margulies I, Liotta L, et al.
Cell
. 1991 Apr;
65(1):25-35.
PMID: 2013093
Reduced expression of the nm23 gene in certain rodent model systems and human breast tumors has been correlated with high tumor metastatic potential. To investigate the functional effects of nm23...
6.
Flatow U, Rabson A, HAND P, Willingham M, Rabson A
Cancer Invest
. 1989 Jan;
7(5):423-35.
PMID: 2695227
We have adapted T24P, a tumorigenic subline of the T24 human bladder cancer cell line, to grow in 5 mM butyrate. In the presence of butyrate, the adapted cells (T24P/B)...
7.
Tagliaferri P, Yanagihara K, Ciardiello F, Talbot N, Flatow U, Benade L, et al.
Int J Cancer
. 1987 Nov;
40(5):653-8.
PMID: 3679592
Both murine and human cell lines transformed by the v-Ki-ras gene have been shown to be much more sensitive to the toxic effects of the cardiac glycoside ouabain than their...
8.
Flatow U, Rabson A, Rabson A
Int J Cancer
. 1987 Aug;
40(2):240-5.
PMID: 3301693
Two sublines of the T24 human urinary bladder carcinoma cell line which differ in tumorigenicity in nude mice have been studied (T24A and T24P). T24A obtained directly from the American...
9.
Flatow U, Willingham M, Rabson A
Cancer Lett
. 1984 Mar;
22(2):203-10.
PMID: 6200208
Since butyrate inhibits DNA synthesis and cell growth, we adapted NIH 3T3 cells to grow in butyrate to study its effects on retroviral cell transformation. In cultures of butyrate-adapted NIH...
10.
Tralka T, Flatow U, Goldstein S, Rabson A
Proc Soc Exp Biol Med
. 1983 Oct;
174(1):41-6.
PMID: 6314342
A cell line derived from hamster spleen transformed by human papovavirus BK was adapted to grow in 5 mM butyrate. Ultrastructurally, the butyrate-adapted cells were found to contain large numbers...