N J Macdonald
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Explore the profile of N J Macdonald including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
519
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Recent Articles
1.
Heylen J, Kemp O, Macdonald N, Mohamedfaris K, Scarborough A, Vats A
Arch Orthop Trauma Surg
. 2021 Feb;
142(8):1769-1773.
PMID: 33586032
Introduction: The majority of neck of femur (NOF) fracture patients are frail and at a higher risk of cardiac arrest. This makes discussion of treatment escalation vital to informed care....
2.
Smith M, Jenkins G, Dean B, ONeill T, Macdonald N
J Small Anim Pract
. 2020 Apr;
61(6):374-380.
PMID: 32323333
Objectives: To investigate the effect of breed as a risk factor associated with humeral condylar fracture in skeletally immature dogs in the UK. Materials And Methods: Retrospective study of dogs...
3.
Ackland G, Abbott T, Cain D, Edwards M, Sultan P, Karmali S, et al.
Br J Anaesth
. 2019 Jan;
122(2):180-187.
PMID: 30686303
Background: Systemic inflammation is pivotal in the pathogenesis of cardiovascular disease. As inflammation can directly cause cardiomyocyte injury, we hypothesised that established systemic inflammation, as reflected by elevated preoperative neutrophil-lymphocyte...
4.
Speake C, Pichugin A, Sahu T, Malkov V, Morrison R, Pei Y, et al.
PLoS One
. 2016 Oct;
11(10):e0165489.
PMID: 27764243
[This corrects the article DOI: 10.1371/journal.pone.0159449.].
5.
Macdonald N, Pettitt R, McConnell J
J Small Anim Pract
. 2011 Oct;
52(11):608-11.
PMID: 22026743
An 8·5-year-old, female, neutered, Rottweiler was presented for investigation of progressive ataxia of one week duration. Proprioception was absent in the left pelvic limb and reduced on the right, thoracolumbar...
6.
Macdonald N, Shivers W, Narum D, Plum S, Wingard J, Fuhrmann S, et al.
J Biol Chem
. 2001 May;
276(27):25190-6.
PMID: 11335715
The mechanism of action of Endostatin, an endogenous inhibitor of angiogenesis and tumor growth, remains unknown. We utilized phage-display technology to identify polypeptides that mimic the binding domains of proteins...
7.
Macdonald N, Decorti F, Pappas T, Taglialatela G
J Anat
. 2001 Feb;
197 Pt 4:543-51.
PMID: 11197527
Age-associated neurodegenerative diseases such as Alzheimer's disease are characterised by neuronal impairment that leads to cognitive deficits. As certain affected neurons depend on trophic factors such as neurotrophins (NTs), impairment...
8.
Sim B, Macdonald N, Gubish E
Cancer Metastasis Rev
. 2001 Feb;
19(1-2):181-90.
PMID: 11191058
Considerable progress has been made in the understanding of the molecular structure and mechanistic aspects of Angiostatin and Endostatin, endogenous angiogenesis inhibitors that have been shown to regress tumors in...
9.
Macdonald N, Taglialatela G
Neuroreport
. 2000 Nov;
11(16):3453-6.
PMID: 11095498
Inducible nitric oxide synthase (iNOS) has been reported in tangle-bearing neurons of patients with Alzheimer's disease (AD), and can be induced by tumor necrosis factor-alpha (TNFalpha). High CNS levels of...
10.
Macdonald N, Murad A, Fogler W, Lu Y, Sim B
Biochem Biophys Res Commun
. 1999 Oct;
264(2):469-77.
PMID: 10529387
Angiostatin protein, which comprises the first four kringle domains of plasminogen, is an endogenous inhibitor of angiogenesis that inhibits the growth of experimental primary and metastatic tumors. Truncation of Angiostatin...