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Tyler Lewy

Explore the profile of Tyler Lewy including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Lercher A, Cheong J, Bale M, Jiang C, Hoffmann H, Ashbrook A, et al.
Immunity . 2024 Oct; 57(11):2530-2546.e13. PMID: 39353439
Pathogen encounter can result in epigenetic remodeling that shapes disease caused by heterologous pathogens. Here, we examined innate immune memory in the context of commonly circulating respiratory viruses. Single-cell analyses...
2.
Le Pen J, Paniccia G, Kinast V, Moncada-Velez M, Ashbrook A, Bauer M, et al.
PLoS Biol . 2024 Sep; 22(9):e3002767. PMID: 39316623
Interferons (IFNs) play a crucial role in the regulation and evolution of host-virus interactions. Here, we conducted a genome-wide arrayed CRISPR knockout screen in the presence and absence of IFN...
3.
Park J, Kim J, Lewy T, Rice C, Elemento O, Rendeiro A, et al.
Genome Biol . 2022 Dec; 23(1):256. PMID: 36514162
Spatial omics technologies enable a deeper understanding of cellular organizations and interactions within a tissue of interest. These assays can identify specific compartments or regions in a tissue with differential...
4.
Lewy T, Hong B, Weiser B, Burger H, Tremain A, Weinstock G, et al.
AIDS Res Hum Retroviruses . 2018 May; 35(3):276-286. PMID: 29808701
Human immunodeficiency virus (HIV)-associated nonacquired immunodeficiency syndrome (AIDS) conditions, such as cardiovascular disease, diabetes, osteoporosis, and dementia are more prevalent in older than in young adult HIV-infected subjects. Although the...