Tsz M Tsang
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Explore the profile of Tsz M Tsang including associated specialties, affiliations and a list of published articles.
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10
Citations
454
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Recent Articles
1.
Ernst A, Ma D, Garcia-Perez I, Tsang T, Kluge W, Schwarz E, et al.
J Proteome Res
. 2012 May;
11(7):3704-14.
PMID: 22613019
Administration of the noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist phencyclidine (PCP) to rodents is widely used as preclinical model for schizophrenia. Most studies on this model employ methods investigating behavior and...
2.
Hradetzky E, Sanderson T, Tsang T, Sherwood J, Fitzjohn S, Lakics V, et al.
Neuropsychopharmacology
. 2011 Sep;
37(2):364-77.
PMID: 21956444
Administration of the DNA-alkylating agent methylazoxymethanol acetate (MAM) on embryonic day 17 (E17) produces behavioral and anatomical brain abnormalities, which model some aspects of schizophrenia. This has lead to the...
3.
McLoughlin G, Ma D, Tsang T, Jones D, Cilia J, Hill M, et al.
J Proteome Res
. 2009 Aug;
8(4):1943-52.
PMID: 19714815
The mechanism of action of standard drug treatments for psychiatric disorders remains fundamentally unknown, despite intensive investigation in academia and the pharmaceutical industry. So far, little is known about the...
4.
Claus S, Tsang T, Wang Y, Cloarec O, Skordi E, Martin F, et al.
Mol Syst Biol
. 2008 Oct;
4:219.
PMID: 18854818
To characterize the impact of gut microbiota on host metabolism, we investigated the multicompartmental metabolic profiles of a conventional mouse strain (C3H/HeJ) (n=5) and its germ-free (GF) equivalent (n=5). We...
5.
Khaitovich P, Lockstone H, Wayland M, Tsang T, Jayatilaka S, Guo A, et al.
Genome Biol
. 2008 Aug;
9(8):R124.
PMID: 18681948
Background: Despite decades of research, the molecular changes responsible for the evolution of human cognitive abilities remain unknown. Comparative evolutionary studies provide detailed information about DNA sequence and mRNA expression...
6.
Huang J, Leweke F, Tsang T, Koethe D, Kranaster L, Gerth C, et al.
PLoS One
. 2007 Aug;
2(8):e756.
PMID: 17712404
Background: The initial prodromal state of psychosis (IPS) is defined as an early disease stage prior to the onset of overt psychosis characterized by sub-threshold or more unspecific psychiatric symptoms....
7.
Holmes E, Tsang T, Huang J, Leweke F, Koethe D, Gerth C, et al.
PLoS Med
. 2006 Aug;
3(8):e327.
PMID: 16933966
Background: The identification of schizophrenia biomarkers is a crucial step towards improving current diagnosis, developing new presymptomatic treatments, identifying high-risk individuals and disease subgroups, and assessing the efficacy of preventative...
8.
Holmes E, Tsang T, Tabrizi S
NeuroRx
. 2006 Jul;
3(3):358-72.
PMID: 16815219
Advances in postgenomic technologies have radically changed the information output from complex biological systems, generating vast amounts of high complexity data that can be interpreted by means of chemometric and...
9.
Tsang T, Huang J, Holmes E, Bahn S
J Proteome Res
. 2006 Apr;
5(4):756-60.
PMID: 16602681
(1)H NMR spectroscopy-based metabonomic analysis was employed to investigate plasma samples from 21 pairs of monozygotic twins discordant for schizophrenia and 8 pairs of age-matched healthy twins in an effort...
10.
Tsang T, Woodman B, McLoughlin G, Griffin J, Tabrizi S, Bates G, et al.
J Proteome Res
. 2006 Mar;
5(3):483-92.
PMID: 16512662
The metabolic consequences of Huntington's disease in the R6/2 mouse model were investigated using NMR spectroscopy and pattern recognition to characterize selected brain regions, muscle, blood, and urine. Global increases...