Paul C Guest
Overview
Explore the profile of Paul C Guest including associated specialties, affiliations and a list of published articles.
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Articles
309
Citations
3380
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Recent Articles
1.
Dudeck L, Nussbaumer M, Nickl-Jockschat T, Guest P, Dobrowolny H, Meyer-Lotz G, et al.
JAMA Psychiatry
. 2025 Mar;
PMID: 40042836
Importance: This study aims to provide robust evidence to support or challenge the immune hypothesis of schizophrenia. Objective: To conduct a meta-analysis of reports on blood leukocyte subpopulations in schizophrenia...
2.
Bernstein H, Nussbaumer M, Vasilevska V, Dobrowolny H, Nickl-Jockschat T, Guest P, et al.
Mol Psychiatry
. 2024 Dec;
30(3):1102-1116.
PMID: 39639174
Dysfunctional glial cells play a pre-eminent role in schizophrenia pathophysiology. Post-mortem studies have provided evidence for significantly decreased glial cell numbers in different brain regions of individuals with schizophrenia. Reduced...
3.
Mukherjee K, Guest P, Schiltz K, Meyer-Lotz G, Dobrowolny H, Borucki K, et al.
J Psychiatr Res
. 2024 Nov;
180:301-306.
PMID: 39486269
The potential influence of astrocytes on neuronal circuitry and psychotic symptoms in schizophrenia have recently been highlighted. Human postmortem studies have observed reduced astrocyte numbers in schizophrenia, but whether this...
4.
Strischewski D, Kalmar A, Guest P, Dobrowolny H, Meyer-Lotz G, Schiffner C, et al.
Eur Arch Psychiatry Clin Neurosci
. 2024 Jun;
275(2):573-579.
PMID: 38851655
Ethanol is metabolized by alcohol dehydrogenase to acetaldehyde and induces cytochrome P450 2E1 (CYP2E1), which generates reactive oxygen species that cause inflammatory liver damage. Clomethiazole, a drug approved for alcohol...
5.
Tzartos J, Karagiorgou K, Pechlivanidou M, Tzartos S, Dudeck L, Meyer-Lotz G, et al.
Schizophr Res
. 2024 Mar;
267:39-41.
PMID: 38518476
No abstract available.
6.
Vasilevska V, Guest P, Szardenings M, Benros M, Steiner J
Transl Psychiatry
. 2024 Mar;
14(1):139.
PMID: 38459000
The global impact of SARS-CoV-2 infection has raised concerns about secondary diseases beyond acute illness. This review explores the significance and potential underlying mechanisms of how SARS-CoV-2 infection might elicit...
7.
Smith B, Guest P, Martins-de-Souza D
Annu Rev Anal Chem (Palo Alto Calif)
. 2024 Feb;
17(1):25-46.
PMID: 38424029
In this review, we discuss the cutting-edge developments in mass spectrometry proteomics and metabolomics that have brought improvements for the identification of new disease-based biomarkers. A special focus is placed...
8.
Guest P, Borgwardt S, Steiner J
Front Psychiatry
. 2024 Jan;
14:1355085.
PMID: 38260772
No abstract available.
9.
Savukoski S, Mannes M, Wohlgemuth L, Schultze A, Guest P, Meyer-Lotz G, et al.
Eur Arch Psychiatry Clin Neurosci
. 2024 Jan;
274(5):1215-1222.
PMID: 38243017
The role of the complement system in schizophrenia (Sz) is inconclusive due to heterogeneity of the disease and study designs. Here, we assessed the levels of complement activation products and...
10.
Guest P, Vasilevska V, Al-Hamadi A, Eder J, Falkai P, Steiner J
Front Psychiatry
. 2024 Jan;
14:1227426.
PMID: 38188049
The sudden appearance and devastating effects of the COVID-19 pandemic resulted in the need for multiple adaptive changes in societies, business operations and healthcare systems across the world. This review...