Tse Wen Chang
Overview
Explore the profile of Tse Wen Chang including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
296
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Recent Articles
1.
Wong M, Lin P, Lin W, Peng C, Wright J, Lee H, et al.
J Med Chem
. 2025 Mar;
PMID: 40044142
Conjugating two fatty acids (2FAs) to peptide drugs can improve pharmacokinetics and therapeutic effects. However, optimizing FA spacing, chain combination, and attachment site to simultaneously enhance albumin binding and drug...
2.
Yu Y, Tian W, Grauffel C, Lin W, Hsieh M, Wu P, et al.
Adv Sci (Weinh)
. 2024 Mar;
11(20):e2307852.
PMID: 38477561
First-line treatment of multiple myeloma, a prevalent blood cancer lacking a cure, using anti-CD38 daratumumab antibody and lenalidomide is often inadequate due to relapse and severe side effects. To enhance...
3.
Chen J, Ramadani F, Pang M, Beavil R, Holdom M, Mitropoulou A, et al.
Sci Rep
. 2018 Aug;
8(1):11548.
PMID: 30069035
Immunoglobulin E (IgE) antibodies play a central role in the allergic response: interaction with FcεRI on mast cells and basophils leads to immediate hypersensitivity reactions upon allergen challenge, while interaction...
4.
Chen J, Lin C, Chen Y, Tian W, Chu H, Chang T
Mol Pharm
. 2017 Sep;
14(11):4113-4120.
PMID: 28954509
Therapeutics reducing bone turnover, such as denosumab (Dmab), an anti-RANKL antibody, can provide treatments for patients with bone destruction. However, some patients with osteoporosis or localized primary bone tumors and...
5.
Allaerts W, Chang T
Acta Biotheor
. 2017 Mar;
65(2):117-134.
PMID: 28342137
The Hygiene Hypothesis has been recognized as an important cornerstone to explain the sudden increase in the prevalence of asthma and allergic diseases in modernized culture. The recent epidemic of...
6.
Chen J, James L, Davies A, Wu Y, Rimmer J, Lund V, et al.
J Allergy Clin Immunol
. 2016 Sep;
139(4):1195-1204.e11.
PMID: 27658758
Background: Chronic rhinosinusitis with nasal polyps is associated with local immunoglobulin hyperproduction and the presence of IgE antibodies against Staphylococcus aureus enterotoxins (SAEs). Aspirin-exacerbated respiratory disease is a severe form...
7.
Liour S, Tom A, Chan Y, Chang T
Pediatr Allergy Immunol
. 2016 Apr;
27(5):446-51.
PMID: 27090058
Targeting the IgE pathway is a clinically validated strategy for treating IgE-mediated diseases. Omalizumab, an anti-IgE antibody, which binds to free IgE and prevents the binding of IgE to FcεRI...
8.
Wright J, Chu H, Huang C, Ma C, Chang T, Lim C
Sci Rep
. 2015 Jun;
5:11581.
PMID: 26113483
Omalizumab, an anti-IgE antibody, used to treat severe allergic asthma and chronic idiopathic urticaria, binds to IgE in blood or membrane-bound on B lymphocytes but not to IgE bound to...
9.
Chang T
Pediatr Allergy Immunol
. 2014 Nov;
25(8):733-9.
PMID: 25378142
Industrial development has advanced at a varying pace in different parts of the world over the past 200 years. Inhabitants of the most industrially advanced regions have experienced major changes...
10.
Chang T, Chen C, Lin C, Metz M, Church M, Maurer M
J Allergy Clin Immunol
. 2014 Jun;
135(2):337-42.
PMID: 24948369
In patients given a diagnosis of chronic spontaneous urticaria (CSU), there are no obvious external triggers, and the factors that initiate the clinical symptoms of wheal, flare, and itch arise...