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Alfur Fu-Hsin Hung

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Articles 8
Citations 69
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Recent Articles
1.
Fan C, Cohen A, Park M, Hung A, Keeffe J, Gnanapragasam P, et al.
Immunity . 2022 Nov; 55(12):2419-2435.e10. PMID: 36370711
Increased immune evasion by SARS-CoV-2 variants of concern highlights the need for new therapeutic neutralizing antibodies. Immunization with nanoparticles co-displaying spike receptor-binding domains (RBDs) from eight sarbecoviruses (mosaic-8 RBD-nanoparticles) efficiently...
2.
Kuo Y, Kuo C, Jenkins K, Hung A, Chang W, Park M, et al.
J Immunother Cancer . 2022 Jun; 10(6). PMID: 35728874
Background: Chimeric antigen receptor (CAR) T cells engineered to recognize and target tumor associated antigens have made a profound impact on the quality of life for many patients with cancer....
3.
Chen N, Hung A, Lin C, Chen J, Chu H, Yu H, et al.
Mol Immunol . 2012 Sep; 53(3):187-97. PMID: 22944457
Surface IgD and IgM doubly positive cells comprise the major population of B cells in the human immune system. The heavy chain of membrane-bound IgD (mδ) differs from that of...
4.
Lin C, Chen N, Chen J, Lu C, Hung A, Shiung Y, et al.
Mol Immunol . 2012 Jun; 52(3-4):190-9. PMID: 22706073
Type-I hypersensitivity reactions play a critical role in the pathogenesis of various allergic diseases. The successful development of the anti-IgE antibody, omalizumab, has validated IgE as an effective therapeutic target...
5.
Shiung Y, Chiang C, Chen J, Wu P, Hung A, Lu D, et al.
Immunobiology . 2012 Jan; 217(7):676-83. PMID: 22226669
A new monoclonal antibody (mAb), specific for human IgE, the central mediator of immediate-type hypersensitivity reactions, has been shown to possess a unique set of binding specificities. The mAb, 8D6,...
6.
Hung A, Chen J, Lu C, Chen N, Yu H, Chang T
Mol Immunol . 2011 Jul; 48(15-16):1975-82. PMID: 21723611
Membrane-bound IgA (mIgA) is associated with Igα/Igβ as the B cell receptor (BCR) complex on mIgA-expressing B cells. The α chain of mIgA (mα) contains a C-terminal membrane-anchor peptide, which...
7.
Chen J, Wu P, Hung A, Chu C, Tsai T, Yu H, et al.
J Immunol . 2010 Jan; 184(4):1748-56. PMID: 20083663
Membrane-bound IgE (mIgE) is part of the IgE-BCR and is essential for generating isotype-specific IgE responses. On mIgE(+) B cells, the membrane-bound epsilon-chain (mepsilon) exists predominantly in the long isoform,...
8.
Hung A, Chen J, Chang T
Mol Immunol . 2008 Jun; 45(13):3624-30. PMID: 18538846
In humans, IgA exists as two subclasses, IgA1 and IgA2, which contain distinct alpha1 and alpha2 heavy chains, respectively. Both subclasses also have membrane-bound forms (mIgA1 and mIgA2) containing the...