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Trevonn M Gyles

Explore the profile of Trevonn M Gyles including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Holt L, Gyles T, Parise E, Minier-Toribio A, Rivera M, Markovic T, et al.
Biol Psychiatry . 2024 Oct; PMID: 39369762
Background: Increasing evidence implicates astrocytes in stress and depression in both rodent models and human major depressive disorder. Despite this, little is known about the transcriptional responses to stress of...
2.
Parise E, Gyles T, Godino A, Sial O, Browne C, Parise L, et al.
bioRxiv . 2024 Apr; PMID: 38659771
Major depressive disorder (MDD) is linked to impaired structural and synaptic plasticity in limbic brain regions. Astrocytes, which regulate synapses and are influenced by chronic stress, likely contribute to these...
3.
Holt L, Gyles T, Parise E, Minier-Toribio A, Markovic T, Rivera M, et al.
bioRxiv . 2024 Jan; PMID: 38293227
Background: Increasing evidence implicates astrocytes in stress and depression in both rodent models and human Major Depressive Disorder (MDD). Despite this, little is known about the transcriptional responses to stress...
4.
Gyles T, Nestler E, Parise E
Neuropsychopharmacology . 2023 Jun; 49(1):215-226. PMID: 37349475
There is an urgent need to develop more effective treatments for stress-related illnesses, which include depression, post-traumatic stress disorder, and anxiety. We view animal models as playing an essential role...
5.
Parise E, Parise L, Sial O, Cardona-Acosta A, Gyles T, Juarez B, et al.
Biol Psychiatry . 2021 Jul; 90(7):482-493. PMID: 34247781
Background: Major depressive disorder is prevalent in children and adolescents and is associated with a high degree of morbidity throughout life, with potentially devastating personal consequences and public health impact....