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Tamara Markovic

Explore the profile of Tamara Markovic including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 225
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Recent Articles
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Wang C, Xue Y, Markovic T, Li H, Wang S, Zhong Y, et al.
Nat Mater . 2025 Feb; PMID: 39962245
The systemic delivery of mRNA molecules to the central nervous system is challenging as they need to cross the blood-brain barrier (BBB) to reach into the brain. Here we design...
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Wang C, Wang S, Xue Y, Zhong Y, Li H, Hou X, et al.
Nat Biotechnol . 2024 Nov; PMID: 39587229
Delivery of biomacromolecules to the central nervous system (CNS) remains challenging because of the restrictive nature of the blood-brain barrier (BBB). We developed a BBB-crossing conjugate (BCC) system that facilitates...
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Holt L, Gyles T, Parise E, Minier-Toribio A, Rivera M, Markovic T, et al.
Biol Psychiatry . 2024 Oct; PMID: 39369762
Background: Increasing evidence implicates astrocytes in stress and depression in both rodent models and human major depressive disorder. Despite this, little is known about the transcriptional responses to stress of...
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Vojvoda Zeljko T, Kajan K, Jalzic B, Hu A, Cukrov N, Margus M, et al.
Environ Microbiome . 2024 Sep; 19(1):67. PMID: 39252078
Background: Antibiotic resistance is a critical global concern, posing significant challenges to human health and medical treatments. Studying antibiotic resistance genes (ARGs) is essential not only in clinical settings but...
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Kwok C, Harding E, Burma N, Markovic T, Massaly N, van den Hoogen N, et al.
Nat Commun . 2024 Jul; 15(1):6264. PMID: 39048565
Opioid withdrawal is a liability of chronic opioid use and misuse, impacting people who use prescription or illicit opioids. Hyperactive autonomic output underlies many of the aversive withdrawal symptoms that...
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Martinez-Rivera F, Yim Y, Godino A, Minier-Toribio A, Tofani S, Holt L, et al.
bioRxiv . 2024 Jul; PMID: 39026727
The development of drug addiction is characterized by molecular changes in brain reward regions that lead to the transition from recreational to compulsive drug use. These neurobiological processes in brain...
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Parise E, Gyles T, Godino A, Sial O, Browne C, Parise L, et al.
bioRxiv . 2024 Apr; PMID: 38659771
Major depressive disorder (MDD) is linked to impaired structural and synaptic plasticity in limbic brain regions. Astrocytes, which regulate synapses and are influenced by chronic stress, likely contribute to these...
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Teague C, Markovic T, Zhou X, Martinez-Rivera F, Minier-Toribio A, Zinsmaier A, et al.
J Neurosci . 2024 Apr; 44(23). PMID: 38637154
Cocaine use disorder is a significant public health issue without an effective pharmacological treatment. Successful treatments are hindered in part by an incomplete understanding of the molecular mechanisms that underlie...
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Markovic T, Higginbotham J, Ruyle B, Massaly N, Yoon H, Kuo C, et al.
Neuropsychopharmacology . 2024 Feb; 49(6):915-923. PMID: 38374364
Opioid use disorder is a chronic relapsing disorder encompassing misuse, dependence, and addiction to opioid drugs. Long term maintenance of associations between the reinforcing effects of the drug and the...