Omar K Sial
Overview
Explore the profile of Omar K Sial including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
190
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Parise E, Gyles T, Godino A, Sial O, Browne C, Parise L, et al.
bioRxiv
. 2024 Apr;
PMID: 38659771
Major depressive disorder (MDD) is linked to impaired structural and synaptic plasticity in limbic brain regions. Astrocytes, which regulate synapses and are influenced by chronic stress, likely contribute to these...
2.
Mitsi V, Ruiz A, Polizu C, Farzinpour Z, Ramakrishnan A, Serafini R, et al.
Mol Pharmacol
. 2024 Feb;
105(4):272-285.
PMID: 38351270
The signal transduction protein, regulator of G protein signaling 4 (RGS4), plays a prominent role in physiologic and pharmacological responses by controlling multiple intracellular pathways. Our earlier work identified the...
3.
Cardona-Acosta A, Sial O, Parise L, Gnecco T, Enriquez Marti G, Bolanos-Guzman C
Sci Rep
. 2023 Jul;
13(1):10872.
PMID: 37407659
Increased use of benzodiazepines in adolescents have been reported, with alprazolam (ALP) being the most abused. Drug abuse during adolescence can induce changes with lasting consequences. This study investigated the...
4.
Maza N, Wang D, Kowalski C, Stoveken H, Dao M, Sial O, et al.
Nat Neurosci
. 2022 Aug;
25(9):1179-1190.
PMID: 35982154
Repeated exposure to opioids causes tolerance, which limits their analgesic utility and contributes to overdose and abuse liability. However, the molecular mechanisms underpinning tolerance are not well understood. Here, we...
5.
Parise L, Parise E, Sial O, Bolanos-Guzman C
Chronic Stress (Thousand Oaks)
. 2022 Jul;
6:24705470221111094.
PMID: 35874910
Background: Individuals who experience emotional, physical, or sexual abuse as children suffer from higher rates of major depressive disorder, drug abuse, and suicide. Early life interventions such as peer support...
6.
Sial O, Gnecco T, Cardona-Acosta A, Vieregg E, Cardoso E, Parise L, et al.
Front Neurosci
. 2021 Aug;
15:701919.
PMID: 34408623
A dramatic increase in the prevalence of major depression and diet-related disorders in adolescents has been observed over several decades, yet the mechanisms underlying this comorbidity have only recently begun...
7.
Parise E, Parise L, Sial O, Cardona-Acosta A, Gyles T, Juarez B, et al.
Biol Psychiatry
. 2021 Jul;
90(7):482-493.
PMID: 34247781
Background: Major depressive disorder is prevalent in children and adolescents and is associated with a high degree of morbidity throughout life, with potentially devastating personal consequences and public health impact....
8.
Parise L, Sial O, Warren B, Sattler C, Duperrouzel J, Parise E, et al.
Psychopharmacology (Berl)
. 2020 Jun;
237(10):3125-3137.
PMID: 32594187
Early life stress influences adult psychopathology and is associated with an increase in the propensity for drug use/seeking throughout the lifespan. Animal models corroborate that stress exposure exacerbates maladaptive reactivity...
9.
Sial O, Parise E, Parise L, Gnecco T, Bolanos-Guzman C
Behav Brain Res
. 2020 Feb;
383:112508.
PMID: 32017978
Two decades ago, the observation of a rapid and sustained antidepressant response after ketamine administration provided an exciting new avenue in the search for more effective therapeutics for the treatment...
10.
Sial O, Warren B, Alcantara L, Parise E, Bolanos-Guzman C
J Neurosci Methods
. 2015 Nov;
258:94-103.
PMID: 26545443
Background: Animal models capable of differentiating the neurobiological intricacies between physical and emotional stress are scarce. Current models rely primarily on physical stressors (e.g., chronic unpredictable or mild stress, social...