Trelia J Craft
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Explore the profile of Trelia J Craft including associated specialties, affiliations and a list of published articles.
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4
Citations
46
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Recent Articles
1.
Franciskovich J, Masters J, Weber W, Klimkowski V, Chouinard M, Sipes P, et al.
Bioorg Med Chem Lett
. 2007 Nov;
17(24):6910-3.
PMID: 17976987
Several P4 domain derivatives of the general d-phenylglycinamide-based scaffold (2) were synthesized and evaluated for their ability to bind to the serine protease factor Xa. Some of the more potent...
2.
Mendel D, Marquart A, Joseph S, Waid P, Yee Y, Tebbe A, et al.
Bioorg Med Chem Lett
. 2007 Jul;
17(17):4832-6.
PMID: 17624775
SAR about the B-ring of a series of N(2)-aroyl anthranilamide factor Xa (fXa) inhibitors is described. B-ring o-aminoalkylether and B-ring p-amine probes of the S1' and S4 sites, respectively, afforded...
3.
Eastwood B, Farmen M, Iversen P, Craft T, Smallwood J, Garbison K, et al.
J Biomol Screen
. 2006 Feb;
11(3):253-61.
PMID: 16490778
The authors show by illustration that procedures used to validate the reliability of single-concentration high-throughput screens such as the signal window and Z' factor do not ensure sufficient reliability in...
4.
Franciskovich J, Masters J, Tinsley J, Craft T, Froelich L, Gifford-Moore D, et al.
Bioorg Med Chem Lett
. 2005 Sep;
15(21):4838-41.
PMID: 16140530
Several non-amidino S1 derivatives of the 1,2-diaminobenzene-based scaffold (4) were synthesized and evaluated for their ability to bind to the active site and inhibit the human protease factor Xa. A...