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Tracey J Mitchell

Explore the profile of Tracey J Mitchell including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 615
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Recent Articles
1.
Jones C, Degasperi A, Grandi V, Amarante T, Mitchell T, Nik-Zainal S, et al.
Sci Rep . 2021 Feb; 11(1):3962. PMID: 33597573
T-cell non-Hodgkin's lymphomas develop following transformation of tissue resident T-cells. We performed a meta-analysis of whole exome sequencing data from 403 patients with eight subtypes of T-cell non-Hodgkin's lymphoma to...
2.
Patel V, Flanagan C, Martins M, Jones C, Butler R, Woollard W, et al.
J Invest Dermatol . 2019 Aug; 140(2):380-389.e4. PMID: 31376383
Phospholipase C Gamma 1 (PLCG1) is frequently mutated in primary cutaneous T-cell lymphoma (CTCL). This study functionally interrogated nine PLCG1 mutations (p.R48W, p.S312L, p.D342N, p.S345F, p.S520F, p.R1158H, p.E1163K, p.D1165H, and...
3.
Butler R, McKenzie R, Jones C, Flanagan C, Woollard W, Demontis M, et al.
J Invest Dermatol . 2019 Mar; 139(9):1975-1984.e2. PMID: 30910759
FK228 (romidepsin) and suberoylanilide hydroxamic acid (vorinostat) are histone deacetylase inhibitors (HDACi) approved by the US Food and Drug Administration for cutaneous T-cell lymphoma (CTCL), including the leukemic subtype Sézary...
4.
Woollard W, Pullabhatla V, Lorenc A, Patel V, Butler R, Bayega A, et al.
Blood . 2016 Apr; 127(26):3387-97. PMID: 27121473
Sézary syndrome (SS) is a leukemic variant of cutaneous T-cell lymphoma (CTCL) and represents an ideal model for study of T-cell transformation. We describe whole-exome and single-nucleotide polymorphism array-based copy...
5.
Boonk S, Zoutman W, Marie-Cardine A, van der Fits L, Out-Luiting J, Mitchell T, et al.
J Invest Dermatol . 2016 Mar; 136(7):1364-1372. PMID: 26930587
Differentiation between Sézary syndrome and erythrodermic inflammatory dermatoses can be challenging, and a number of studies have attempted to identify characteristic immunophenotypic changes and molecular biomarkers in Sézary cells that...
6.
Woollard W, Kalaivani N, Jones C, Roper C, Tung L, Lee J, et al.
J Invest Dermatol . 2016 Feb; 136(6):1238-1246. PMID: 26872600
Methylthioadenosine phosphorylase (MTAP) and the tumor suppressor genes CDKN2A-CDKN2B are frequently deleted in malignancies. The specific role of MTAP in cutaneous T-cell lymphoma subgroups, mycosis fungoides (MF) and Sézary syndrome...
7.
Jones C, Ferreira S, McKenzie R, Tosi I, Caesar J, Bagot M, et al.
J Invest Dermatol . 2012 Apr; 132(8):2042-9. PMID: 22495182
T-plastin (PLS3) is an actin-bundling protein normally expressed in epithelial cells but absent in cells of hematopoietic origin. Aberrant PLS3 expression has been demonstrated in lymphocytes from Sézary syndrome (SS)...
8.
Agar N, Wedgeworth E, Crichton S, Mitchell T, Cox M, Ferreira S, et al.
J Clin Oncol . 2010 Sep; 28(31):4730-9. PMID: 20855822
Purpose: We have analyzed the outcome of mycosis fungoides (MF) and Sézary syndrome (SS) patients using the recent International Society for Cutaneous Lymphomas (ISCL)/European Organisation for Research and Treatment of...
9.
Jones C, Wain E, Chu C, Tosi I, Foster R, McKenzie R, et al.
J Invest Dermatol . 2009 Sep; 130(4):1116-25. PMID: 19759548
Sézary Syndrome (SS) is an aggressive leukemic variant of primary cutaneous T-cell lymphoma characterized by the presence of tumor or Sézary cells that generally display a mature memory T-cell immunophenotype....
10.
Senff N, Zoutman W, Vermeer M, Assaf C, Berti E, Cerroni L, et al.
J Invest Dermatol . 2008 Nov; 129(5):1149-55. PMID: 19020554
Primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL, LT) is the most aggressive type of primary cutaneous B-cell lymphoma. In a recent study on 12 patients it was found...