Toni Schumacher
Overview
Explore the profile of Toni Schumacher including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
597
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0
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Recent Articles
1.
Schumacher T, Reyer H, Maak S, Rontgen M
Front Vet Sci
. 2023 Dec;
10:1028879.
PMID: 38099002
Introduction: Porcine congenital splay leg syndrome (PCS) is a major birth defect in piglets, resulting in lameness and high mortality rates. The multifactorial pathogenesis of PSC is not well understood...
2.
Stange K, Schumacher T, Miersch C, Whelan R, Klunemann M, Rontgen M
Curr Issues Mol Biol
. 2023 May;
45(4):2661-2680.
PMID: 37185698
An optimal supply of L-methionine (L-Met) improves muscle growth, whereas over-supplementation exerts adverse effects. To understand the underlying mechanisms, this study aims at exploring effects on the growth, viability, ROS...
3.
Schumacher T, Rontgen M, Maak S
Front Vet Sci
. 2021 Mar;
8:609883.
PMID: 33718467
The porcine congenital splay leg syndrome (PCS), even though being of transient nature, is still one of the most important causes for piglet losses due to its high incidence and...
4.
Goody D, Gupta S, Engelmann D, Spitschak A, Marquardt S, Mikkat S, et al.
Theranostics
. 2019 Mar;
9(5):1490-1509.
PMID: 30867845
Metastasis management remains a long-standing challenge. High abundance of E2F1 triggers tumor progression by developing protein-protein interactions (PPI) with coregulators that enhance its potential to activate a network of prometastatic...
5.
Rakers C, Schleif M, Blank N, Matuskova H, Ulas T, Handler K, et al.
Glia
. 2018 Dec;
67(4):619-633.
PMID: 30585358
Astrocytes support normal brain function, but may also contribute to neurodegeneration when they become reactive under pathological conditions such as stroke. However, the molecular underpinnings of this context-dependent interplay between...
6.
Furst K, Steder M, Logotheti S, Angerilli A, Spitschak A, Marquardt S, et al.
Cancer Lett
. 2018 Nov;
442:299-309.
PMID: 30445206
Melanoma is an aggressive cancer with poor prognosis, requiring personalized management of advanced stages and establishment of molecular markers. Melanomas derive from melanocytes, which specifically express tyrosinase, the rate-limiting enzyme...
7.
Schumacher T, Benndorf R
Molecules
. 2017 Apr;
22(4).
PMID: 28383515
Adenosine triphosphate (ATP)-binding cassette (ABC) transporters may play an important role in the pathogenesis of atherosclerotic vascular diseases due to their involvement in cholesterol homeostasis, blood pressure regulation, endothelial function,...
8.
Saggu R, Schumacher T, Gerich F, Rakers C, Tai K, Delekate A, et al.
Acta Neuropathol Commun
. 2016 Aug;
4(1):76.
PMID: 27487766
Vascular cognitive impairment is the second most common form of dementia. The pathogenic pathways leading to vascular cognitive impairment remain unclear but clinical and experimental data have shown that chronic...
9.
Hofrichter J, Krohn M, Schumacher T, Lange C, Feistel B, Walbroel B, et al.
J Alzheimers Dis
. 2016 Jun;
53(3):967-80.
PMID: 27258424
Nowadays, Alzheimer's disease is the most prevalent epiphenomenon of the aging population. Although soluble amyloid-β (Aβ) species (monomers, oligomers) are recognized triggers of the disease, no therapeutic approach is able...
10.
Krohn M, Bracke A, Avchalumov Y, Schumacher T, Hofrichter J, Paarmann K, et al.
Brain
. 2015 May;
138(Pt 8):2370-82.
PMID: 25991605
Amyloidosis mouse models of Alzheimer's disease are generally established by transgenic approaches leading to an overexpression of mutated human genes that are known to be involved in the generation of...