Thomas Bruning
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Explore the profile of Thomas Bruning including associated specialties, affiliations and a list of published articles.
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526
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11644
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Recent Articles
1.
Hoppe R, Winter S, Lo W, Michailidou K, Bolla M, Keeman R, et al.
NPJ Breast Cancer
. 2025 Feb;
11(1):18.
PMID: 39971965
The role of germline genetics in adjuvant aromatase inhibitor (AI) treatment efficacy in ER-positive breast cancer is poorly understood. We employed a two-stage candidate gene approach to examine associations between...
2.
Santos-Garcia I, Bascunana P, Brackhan M, Villa M, Eiriz I, Bruning T, et al.
Alzheimers Res Ther
. 2025 Jan;
17(1):30.
PMID: 39871385
Background: Specific genetic variants in the ATP-binding cassette transporter A7 locus (ABCA7) are associated with an increased risk of Alzheimer's disease (AD). ABCA7 transports lipids from/across cell membranes, regulates Aβ...
3.
Koslitz S, Taeger D, Heinrich B, Koster D, Pelzl T, Kafferlein H, et al.
J Occup Environ Hyg
. 2025 Jan;
22(1):52-61.
PMID: 39745860
Firefighters are exposed to a variety of hazardous substances during firefighting activities. Fire smoke contains polycyclic aromatic hydrocarbons (PAHs) some of which have been shown to cause cancer in humans....
4.
Wu J, Santos-Garcia I, Eiriz I, Bruning T, Kvasnicka A, Friedecky D, et al.
Pharmacol Res
. 2024 Dec;
211():107557.
PMID: 39725338
Huntington's disease (HD) is a debilitating neurodegenerative disorder characterized by severe motor deficits, cognitive decline and psychiatric disturbances. An early and significant morphological hallmark of HD is the activation of...
5.
Kasper-Sonnenberg M, Palmke C, Wrobel S, Bruning T, Murawski A, Apel P, et al.
Environ Int
. 2024 Dec;
195():109190.
PMID: 39693778
The German Environmental Specimen Bank (ESB) annually archives 24-h urine samples since the early 1980s. In this study, we analyzed 420 of these samples from the years 2014 to 2022...
6.
Lang K, Kohler C, Wichert K, Deix T, Bartsch G, Sommer G, et al.
J Transl Med
. 2024 Nov;
22(1):1061.
PMID: 39587670
Background: For more than 80 years, cystoscopy has been the gold standard for identification of urothelial carcinoma (UCa). Because of many factors, such as pain of the patients during this...
7.
Hovanec J, Kendzia B, Olsson A, Schuz J, Kromhout H, Vermeulen R, et al.
Epidemiology
. 2024 Oct;
36(2):245-252.
PMID: 39435907
Background: Increased lung cancer risks for low socioeconomic status (SES) groups are only partially attributable to smoking habits. Little effort has been made to investigate the persistent risks related to...
8.
van Kampen V, Theile A, Tannapfel A, Eisenhawer C, Bruning T, Merget R
Allergol Select
. 2024 Aug;
8:283-292.
PMID: 39211357
Hypersensitivity pneumonitis (HP) is a rare, mostly occupational allergic disease of the lungs. There are many inhalable antigens that can cause HP. Most are organic dusts, rarely chemicals. A clinical...
9.
Gorska A, Santos-Garcia I, Eiriz I, Bruning T, Nyman T, Pahnke J
J Neurosci Methods
. 2024 Aug;
411:110239.
PMID: 39102902
Background: Mass spectrometry (MS)-based cerebrospinal fluid (CSF) proteomics is an important method for discovering biomarkers of neurodegenerative diseases. CSF serves as a reservoir for interstitial fluid (ISF), and extensive communication...
10.
Davidson A, Michailidou K, Parsons M, Fortuno C, Bolla M, Wang Q, et al.
Am J Hum Genet
. 2024 Aug;
111(9):2059-2069.
PMID: 39096911
Co-observation of a gene variant with a pathogenic variant in another gene that explains the disease presentation has been designated as evidence against pathogenicity for commonly used variant classification guidelines....