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Tomonari Sasazuki

Explore the profile of Tomonari Sasazuki including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 347
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Recent Articles
1.
Sawada T, Nishiyama C, Kishi T, Sasazuki T, Komazawa-Sakon S, Xue X, et al.
J Biol Chem . 2008 Aug; 283(39):26820-8. PMID: 18667423
OTT/RBM15-BSAC/MAL/MKL1/MRTF-A was identified as a fusion transcript generated by t(1;22)(p13;q13) in acute megakaryoblastic leukemia. Previous studies have shown that BSAC (basic, SAP, and coiled-coil domain) activates the promoters containing CArG...
2.
Nakajima A, Komazawa-Sakon S, Takekawa M, Sasazuki T, Yeh W, Yagita H, et al.
EMBO J . 2006 Nov; 25(23):5549-59. PMID: 17110930
Inhibition of NF-kappaB activation increases susceptibility to tumor necrosis factor (TNF)alpha-induced cell death, concurrent with caspases and prolonged c-Jun N-terminal kinase (JNK) activation, and reactive oxygen species (ROS) accumulation. However,...
3.
Sasazuki T, Okazaki T, Tada K, Sakon-Komazawa S, Katano M, Tanaka M, et al.
Mol Immunol . 2004 Jun; 41(5):547-51. PMID: 15183933
We recently showed that TNF induces accumulation of reactive oxygen species (ROS) that mediates necrosis in murine embryonic fibroblasts (MEFs) derived from TRAF2- and TRAF5-double deficient (DKO) mice. To elucidate...
4.
Sakon S, Xue X, Takekawa M, Sasazuki T, Okazaki T, Kojima Y, et al.
EMBO J . 2003 Jul; 22(15):3898-909. PMID: 12881424
NF-kappaB downregulates tumor necrosis factor (TNF)-induced c-Jun N-terminal kinase (JNK) activation that promotes cell death, but the mechanism is not yet fully understood. By using murine embryonic fibroblasts (MEFs) that...
5.
Okazaki T, Sakon S, Sasazuki T, Sakurai H, Doi T, Yagita H, et al.
Biochem Biophys Res Commun . 2003 Feb; 300(4):807-12. PMID: 12559944
Phosphorylation of several serine residues especially in the transactivation (TA) domain of p65 NF-kappaB subunit has been suggested to be important for its transcriptional activity. However, the responsible phosphorylation site...
6.
Sasazuki T, Sawada T, Sakon S, Kitamura T, Kishi T, Okazaki T, et al.
J Biol Chem . 2002 May; 277(32):28853-60. PMID: 12019265
Tumor necrosis factor (TNF) is a multifunctional cytokine, which induces proliferation or death in a cell type-dependent manner. We previously showed that murine embryonic fibroblasts (MEFs) from TNF receptor-associated factor...