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Ko Okumura

Explore the profile of Ko Okumura including associated specialties, affiliations and a list of published articles. Areas
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Articles 465
Citations 10451
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Recent Articles
1.
Peng G, Zhao W, Abudouwanli A, Sun Q, Yang M, Wang S, et al.
Allergol Int . 2025 Feb; PMID: 39986986
Background: Atopic dermatitis (AD), a prevalent chronic inflammatory skin disorder, is characterized by compromised skin barrier and heightened immune responses. The study investigates the therapeutic efficacy of catestatin (CST), a...
2.
Oishi K, Nakano N, Ota M, Inage E, Izawa K, Kaitani A, et al.
Allergy . 2025 Jan; PMID: 39868907
Background: IgE-mediated food allergy is accompanied by mucosal mast cell (MMC) hyperplasia in the intestinal mucosa. Intestinal MMC numbers correlate with the severity of food allergy symptoms. However, the mechanisms...
3.
Harada S, Kato M, Nakagome K, Sasano H, Tanabe Y, Takeshige T, et al.
Biomolecules . 2025 Jan; 15(1). PMID: 39858516
Diffuse interstitial lung diseases (ILD) include conditions with identifiable causes such as chronic eosinophilic pneumonia (CEP), sarcoidosis (SAR), chronic hypersensitivity pneumonitis (CHP), and connective tissue disease-associated interstitial pneumonia (CTD), as...
4.
Nagamine M, Kaitani A, Izawa K, Ando T, Yoshikawa A, Nakamura M, et al.
Front Immunol . 2024 Dec; 15:1477072. PMID: 39640264
Mas-related G protein-coupled receptor b2 (Mrgprb2) binding to its cationic endogenous and exogenous ligands induces mast cell degranulation and promotes inflammation in mice. However, the physiological roles of its human...
5.
Takeda K, Nakayama M, Hayakawa Y, Kojima Y, Ikeda H, Imai N, et al.
Nat Commun . 2024 Dec; 15(1):10558. PMID: 39632790
No abstract available.
6.
Harada S, Sasano H, Ueda S, Sandhu Y, Abe S, Tanabe Y, et al.
J Asthma Allergy . 2024 Nov; 17:1103-1113. PMID: 39524483
Background: Examining human coding and non-coding RNAs present in skin surface lipids (SSL-RNAs) offers a promising approach to understanding the physiological state of the skin. Benralizumab treatment can reduce exacerbations...
7.
Numata T, Ikutani M, Arae K, Ohno T, Okada K, Yoshimoto T, et al.
Sci Rep . 2024 Nov; 14(1):26706. PMID: 39496822
Mast cells (MCs) are tissue-resident cells of hematopoietic origin that play an important role in host's defense mechanism against nematodes. However, excessive activation of these cells contributes to the development...
8.
Sendai Y, Takeda K, Ohta K, Nakae S, Koshika K, Kitamura K, et al.
Int Immunol . 2024 Oct; 37(4):221-234. PMID: 39460731
Translocator protein (TSPO) is a mitochondrial outer membrane protein expressed on a variety of immune cells, including macrophages, dendritic cells, and T cells, in addition to neurons and steroid-producing cells....
9.
Sato Y, Sasano H, Abe S, Sandhu Y, Ueda S, Harada S, et al.
Curr Issues Mol Biol . 2024 Oct; 46(10):11425-11437. PMID: 39451560
The analysis of skin surface lipid-RNAs (SSL-RNAs) provides a non-invasive method for understanding the molecular pathology of atopic dermatitis (AD), but its relevance to asthma remains uncertain. Although dupilumab, a...
10.
Ohara A, Okumura K
Soft Matter . 2024 Oct; 20(43):8589-8600. PMID: 39417415
Due to the advent of various foldable electric devices, it is becoming increasingly important to understand the bending properties of film materials. Bending of isotropic materials may be trivial if...