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Tomomi Hikosaka

Explore the profile of Tomomi Hikosaka including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 63
Followers 0
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Recent Articles
1.
Nakashima K, Inatsu H, Kitamura K, Hikosaka T, Hoshiko S, Ashiduka S
Clin J Gastroenterol . 2015 Jul; 5(6):373-6. PMID: 26181316
A 64-year-old man diagnosed with advanced malignant peritoneal mesothelioma by laparoscopic biopsy was treated with systemic chemotherapy. The patient underwent first-line chemotherapy with pemetrexed plus cisplatin for 11 months, then...
2.
Izawa N, Onozawa Y, Hikosaka T, Hamauchi S, Tsushima T, Todaka A, et al.
Int J Clin Oncol . 2014 Sep; 20(3):455-62. PMID: 25248339
Background: We evaluated the efficacy and feasibility of docetaxel, cisplatin, and 5-fluorouracil (TPF) induction chemotherapy followed by concurrent chemoradiotherapy (CRT) for locally advanced head and neck squamous cell carcinoma (HNSCC)...
3.
Hikosaka T, Yamazaki K
Gan To Kagaku Ryoho . 2013 Dec; 40(11):1456-8. PMID: 24319791
No abstract available.
4.
Kuwasako K, Hay D, Nagata S, Hikosaka T, Kitamura K, Kato J
Br J Pharmacol . 2011 Dec; 166(1):137-50. PMID: 22142144
Background And Purpose: The extracellular loops (ECLs) in Family A GPCRs are important for ligand binding and receptor activation, but little is known about the function of Family B GPCR...
5.
Hikosaka T, Tsuruda T, Nagata S, Kuwasako K, Tsuchiya K, Hoshiko S, et al.
Peptides . 2011 Aug; 32(9):1825-31. PMID: 21839130
Adrenomedullin (AM) is highly expressed in various cancer cell lines, suggesting a possible association with cancer growth. In the present study, we examined the expression and/or concentration of AM, its...
6.
Kuwasako K, Kitamura K, Nagata S, Hikosaka T, Takei Y, Kato J
Peptides . 2011 Jun; 32(7):1540-50. PMID: 21645567
Adrenomedullin (AM) is a novel hypotensive peptide that exerts a variety of strongly protective effects against multiorgan damage. AM-specific receptors were first identified as heterodimers composed of calcitonin-receptor-like receptor (CLR),...
7.
Kuwasako K, Kitamura K, Nagata S, Hikosaka T, Kato J
Peptides . 2010 Oct; 32(1):144-9. PMID: 20946927
Adrenomedullin 1 (AM(1)) receptor is a heterodimer composed of calcitonin receptor-like receptor (CLR) - a family B G protein-coupled receptor (GPCR) - and receptor activity-modifying protein 2 (RAMP2). Both family...
8.
Kuwasako K, Kitamura K, Nagata S, Hikosaka T, Kato J
Biochem Biophys Res Commun . 2010 Jan; 392(3):380-5. PMID: 20074556
Receptor activity-modifying protein 2 (RAMP2) enables calcitonin receptor-like receptor (CRLR) to form an adrenomedullin (AM)-specific receptor. Here we investigated the function of the cytoplasmic C-terminal tail (C-tail) of human (h)CRLR...