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Tomoko Nagino

Explore the profile of Tomoko Nagino including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 108
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Recent Articles
1.
Takada H, Kaieda A, Tawada M, Nagino T, Sasa K, Oikawa T, et al.
J Med Chem . 2019 Sep; 62(20):9175-9187. PMID: 31550153
Dysferlinopathies, which are muscular diseases caused by mutations in the dysferlin gene, remain serious medical problems due to the lack of therapeutic agents. Herein, we report the design, synthesis, and...
2.
Kokubu Y, Nagino T, Sasa K, Oikawa T, Miyake K, Kume A, et al.
Stem Cells Transl Med . 2019 Jun; 8(10):1017-1029. PMID: 31250983
Dysferlinopathy is a progressive muscle disorder that includes limb-girdle muscular dystrophy type 2B and Miyoshi myopathy (MM). It is caused by mutations in the dysferlin (DYSF) gene, whose function is...
3.
Suzuki T, Nishi T, Nagino T, Sasaki K, Aizawa K, Kada N, et al.
J Biol Chem . 2007 Feb; 282(13):9895-9901. PMID: 17283079
Krüppel-like factor 5 (KLF5) is a transcription factor important in regulation of the cardiovascular response to external stress. KLF5 regulates pathological cell growth, and its acetylation is important for this...
4.
Miyamoto S, Suzuki T, Muto S, Aizawa K, Kimura A, Mizuno Y, et al.
Mol Cell Biol . 2003 Nov; 23(23):8528-41. PMID: 14612398
Here we show a novel pathway of transcriptional regulation of a DNA-binding transcription factor by coupled interaction and modification (e.g., acetylation) through the DNA-binding domain (DBD). The oncogenic regulator SET...