Yuko Kokubu
Overview
Explore the profile of Yuko Kokubu including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
1563
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0
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Recent Articles
1.
Ng Y, Chanda S, Janas J, Yang N, Kokubu Y, Sudhof T, et al.
Stem Cell Reports
. 2021 Jun;
16(7):1763-1776.
PMID: 34171286
The differentiation of pluripotent stem cells can be accomplished by sequential activation of signaling pathways or through transcription factor programming. Multistep differentiation imitates embryonic development to obtain authentic cell types,...
2.
Takada H, Kaieda A, Tawada M, Nagino T, Sasa K, Oikawa T, et al.
J Med Chem
. 2019 Sep;
62(20):9175-9187.
PMID: 31550153
Dysferlinopathies, which are muscular diseases caused by mutations in the dysferlin gene, remain serious medical problems due to the lack of therapeutic agents. Herein, we report the design, synthesis, and...
3.
Kokubu Y, Nagino T, Sasa K, Oikawa T, Miyake K, Kume A, et al.
Stem Cells Transl Med
. 2019 Jun;
8(10):1017-1029.
PMID: 31250983
Dysferlinopathy is a progressive muscle disorder that includes limb-girdle muscular dystrophy type 2B and Miyoshi myopathy (MM). It is caused by mutations in the dysferlin (DYSF) gene, whose function is...
4.
Shimbo M, Kudo T, Hamada M, Jeon H, Imamura Y, Asano K, et al.
Exp Anim
. 2016 Jan;
65(2):175-87.
PMID: 26822934
The Japan Aerospace Exploration Agency developed the mouse Habitat Cage Unit (HCU) for installation in the Cell Biology Experiment Facility (CBEF) onboard the Japanese Experimental Module ("Kibo") on the International...
5.
Kokubu Y, Asashima M, Kurisaki A
Biochem Biophys Res Commun
. 2015 Jun;
463(4):1218-24.
PMID: 26086106
The pituitary gland is a center of the endocrine system that controls homeostasis in an organism by secreting various hormones. The glandular anterior pituitary consists of five different cell types,...
6.
Kowno M, Watanabe-Susaki K, Ishimine H, Komazaki S, Enomoto K, Seki Y, et al.
PLoS One
. 2014 Apr;
9(4):e81552.
PMID: 24709813
Background: The pluripotent state of embryonic stem (ES) cells is controlled by a network of specific transcription factors. Recent studies also suggested the significant contribution of mitochondria on the regulation...
7.
Vierbuchen T, Ostermeier A, Pang Z, Kokubu Y, Sudhof T, Wernig M
Nature
. 2010 Jan;
463(7284):1035-41.
PMID: 20107439
Cellular differentiation and lineage commitment are considered to be robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent...