Tomo Saric
Overview
Explore the profile of Tomo Saric including associated specialties, affiliations and a list of published articles.
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82
Citations
2754
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Recent Articles
1.
Kayser A, Dittmann S, Saric T, Mearini G, Verkerk A, Schulze-Bahr E
Int J Mol Sci
. 2023 Oct;
24(20).
PMID: 37894977
Mutations in the gene, encoding one of the major subunits of cardiac G-protein-gated inwardly rectifying K (GIRK) channels, have been recently linked to inherited forms of sinus node dysfunction. Here,...
2.
Kayser A, Dittmann S, van Impel A, Saric T, Schulze-Bahr E
Stem Cell Res
. 2023 Oct;
73:103223.
PMID: 37890333
A published heterozygous gain-of-function variant in the KCNJ5 gene (p.Trp101Cys) encoding the G-protein-activated inward-rectifier potassium channel 4 subunit of the I channel is associated with human sinus node dysfunction (SND)....
3.
Xu G, Fatima A, Breitbach M, Kuzmenkin A, Fugemann C, Ivanyuk D, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047520
Most cardiomyocytes (CMs) in the adult mammalian heart are either binucleated or contain a single polyploid nucleus. Recent studies have shown that polyploidy in CMs plays an important role as...
4.
Chirico N, Kessler E, Maas R, Fang J, Qin J, Dokter I, et al.
Stem Cell Res Ther
. 2022 Dec;
13(1):531.
PMID: 36575473
Background: Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (iPSC-CMs) do not display all hallmarks of mature primary cardiomyocytes, especially the ability to use fatty acids (FA) as an energy source,...
5.
Peters M, Maas R, van Adrichem I, Doevendans P, Mercola M, Saric T, et al.
Stem Cells Transl Med
. 2022 Aug;
11(10):1040-1051.
PMID: 36018047
The development of new cardioprotective approaches using in vivo models of ischemic heart disease remains challenging as differences in cardiac physiology, phenotype, and disease progression between humans and animals influence...
6.
Neef K, Drey F, Lepperhof V, Wahlers T, Hescheler J, Choi Y, et al.
Front Cardiovasc Med
. 2022 Jan;
8:794690.
PMID: 35071360
Induced pluripotent stem cell-derived cardiomyocytes (iPS-CMs) represent an attractive resource for cardiac regeneration. However, survival and functional integration of transplanted iPS-CM is poor and remains a major challenge for the...
7.
Khodayari H, Khodayari S, Ebrahimi E, Hadjilooei F, Vesovic M, Mahmoodzadeh H, et al.
Cancer Immunol Immunother
. 2021 Jul;
70(12):3369-3395.
PMID: 34218295
Nowadays, natural killer (NK) cell-based immunotherapy provides a practical therapeutic strategy for patients with advanced solid tumors (STs). This approach is adaptively conducted by the autologous and identical NK cells...
8.
Lima Cunha D, Oram A, Gruber R, Plank R, Lingenhel A, Gupta M, et al.
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33670118
Inherited ichthyoses represent a large heterogeneous group of skin disorders characterised by impaired epidermal barrier function and disturbed cornification. Current knowledge about disease mechanisms has been uncovered mainly through the...
9.
Burkert K, Taheri H, Hamad S, Oliverio M, Peinkofer G, Kornfeld J, et al.
Sci Rep
. 2021 Jan;
11(1):2391.
PMID: 33504837
Clinical translation of pluripotent stem cell (PSC) derivatives is hindered by the tumorigenic risk from residual undifferentiated cells. Here, we identified salicylic diamines as potent agents exhibiting toxicity to murine...
10.
Peinkofer G, Maass M, Pfannkuche K, Sachinidis A, Baldus S, Hescheler J, et al.
Stem Cell Res Ther
. 2021 Jan;
12(1):46.
PMID: 33419458
Background: Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) are regarded as promising cell type for cardiac cell replacement therapy, but it is not known whether the developmental stage influences their persistence...