Tommaso Cavazza
Overview
Explore the profile of Tommaso Cavazza including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
14
Citations
357
Followers
0
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Recent Articles
1.
Magerl B, Cavazza T
Nat Struct Mol Biol
. 2025 Jan;
32(2):217-219.
PMID: 39843981
No abstract available.
2.
Jentoft I, Bauerlein F, Welp L, Cooper B, Petrovic A, So C, et al.
Cell
. 2023 Nov;
186(24):5308-5327.e25.
PMID: 37922900
Mammalian oocytes are filled with poorly understood structures called cytoplasmic lattices. First discovered in the 1960s and speculated to correspond to mammalian yolk, ribosomal arrays, or intermediate filaments, their function...
3.
4.
Kletter T, Reusch S, Cavazza T, Dempewolf N, Tischer C, Reber S
J Cell Biol
. 2021 Nov;
221(1).
PMID: 34787651
The function of cellular structures at the mesoscale is dependent on their geometry and proportionality to cell size. The mitotic spindle is a good example why length and shape of...
5.
Cavazza T, Takeda Y, Politi A, Aushev M, Aldag P, Baker C, et al.
Cell
. 2021 May;
184(11):2860-2877.e22.
PMID: 33964210
Most human embryos are aneuploid. Aneuploidy frequently arises during the early mitotic divisions of the embryo, but its origin remains elusive. Human zygotes that cluster their nucleoli at the pronuclear...
6.
Scheffler K, Uraji J, Jentoft I, Cavazza T, Monnich E, Mogessie B, et al.
Nat Commun
. 2021 Feb;
12(1):841.
PMID: 33547291
A new life begins with the unification of the maternal and paternal chromosomes upon fertilization. The parental chromosomes first become enclosed in two separate pronuclei near the surface of the...
7.
Thomas C, Cavazza T, Schuh M
Biochem Soc Trans
. 2021 Jan;
49(1):107-118.
PMID: 33449109
Human eggs frequently contain an incorrect number of chromosomes, a condition termed aneuploidy. Aneuploidy affects ∼10-25% of eggs in women in their early 30s, and more than 50% of eggs...
8.
Rosas-Salvans M, Cavazza T, Espadas G, Sabido E, Vernos I
Mol Cell Proteomics
. 2018 Jul;
17(10):1991-2004.
PMID: 29970457
Microtubules (MTs) and associated proteins can self-organize into complex structures such as the bipolar spindle, a process in which RanGTP plays a major role. Addition of RanGTP to M-phase egg...
9.
Cavazza T, Malgaretti P, Vernos I
Mol Biol Cell
. 2016 Aug;
27(19):2935-45.
PMID: 27489339
Centrosome maturation is the process by which the duplicated centrosomes recruit pericentriolar components and increase their microtubule nucleation activity before mitosis. The role of this process in cells entering mitosis...
10.
Burgess S, Oleksy A, Cavazza T, Richards M, Vernos I, Matthews D, et al.
Open Biol
. 2016 Jul;
6(7).
PMID: 27411893
The vast majority of clinically approved protein kinase inhibitors target the ATP-binding pocket directly. Consequently, many inhibitors have broad selectivity profiles and most have significant off-target effects. Allosteric inhibitors are...