Stressful Start Causes Chromosome Errors in Human Embryos
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Citing Articles
Negotiating the space and time conundrum in human zygotes: chaos theory in action.
Albertini D J Assist Reprod Genet. 2025; 42(1):1-2.
PMID: 39883301 PMC: 11806122. DOI: 10.1007/s10815-025-03407-7.
Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryos.
McCoy R, Summers M, McCollin A, Ottolini C, Ahuja K, Handyside A Genome Med. 2023; 15(1):77.
PMID: 37779206 PMC: 10544495. DOI: 10.1186/s13073-023-01231-1.
References
1.
Palmerola K, Amrane S, De Los Angeles A, Xu S, Wang N, de Pinho J
. Replication stress impairs chromosome segregation and preimplantation development in human embryos. Cell. 2022; 185(16):2988-3007.e20.
DOI: 10.1016/j.cell.2022.06.028.
View
2.
Gaillard H, Garcia-Muse T, Aguilera A
. Replication stress and cancer. Nat Rev Cancer. 2015; 15(5):276-89.
DOI: 10.1038/nrc3916.
View
3.
Deng L, Wu R, Sonneville R, Kochenova O, Labib K, Pellman D
. Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements. Mol Cell. 2019; 73(5):915-929.e6.
PMC: 6410736.
DOI: 10.1016/j.molcel.2018.12.021.
View
4.
Babariya D, Fragouli E, Alfarawati S, Spath K, Wells D
. The incidence and origin of segmental aneuploidy in human oocytes and preimplantation embryos. Hum Reprod. 2017; 32(12):2549-2560.
DOI: 10.1093/humrep/dex324.
View
5.
Girardi L, Serdarogullari M, Patassini C, Poli M, Fabiani M, Caroselli S
. Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos. Am J Hum Genet. 2020; 106(4):525-534.
PMC: 7118577.
DOI: 10.1016/j.ajhg.2020.03.005.
View