Isabelle Vernos
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Explore the profile of Isabelle Vernos including associated specialties, affiliations and a list of published articles.
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68
Citations
2266
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Recent Articles
1.
Karamtzioti P, Ferrer-Vaquer A, Barragan M, Vernos I, Vassena R, Tiscornia G
Reprod Biomed Online
. 2025 Feb;
:103885.
PMID: 39920028
Research Question: What are the profiles of tubulin post-translational modifications (PTM) in the meiotic spindles of oocytes with different developmental competence: in-vivo matured MII oocytes (IVO) versus cumulus-free in-vitro matured...
2.
Verrillo G, Obeid A, Genco A, Scrofani J, Orange F, Hanache S, et al.
J Cell Sci
. 2024 Apr;
137(9).
PMID: 38661008
DPF3, along with other subunits, is a well-known component of the BAF chromatin remodeling complex, which plays a key role in regulating chromatin remodeling activity and gene expression. Here, we...
3.
Scrofani J, Ruhnow F, Chew W, Normanno D, Nedelec F, Surrey T, et al.
Mol Biol Cell
. 2023 Nov;
35(1):ar12.
PMID: 37991893
Chromosome segregation relies on the correct assembly of a bipolar spindle. Spindle pole self-organization requires dynein-dependent microtubule (MT) transport along other MTs. However, during M-phase RanGTP triggers MT nucleation and...
4.
Zadra I, Jimenez-Delgado S, Anglada-Girotto M, Segura-Morales C, Compton Z, Janke C, et al.
Nat Commun
. 2022 Nov;
13(1):7147.
PMID: 36414642
Regulation of microtubule (MT) dynamics is key for mitotic spindle assembly and faithful chromosome segregation. Here we show that polyglutamylation, a still understudied post-translational modification of spindle MTs, is essential...
5.
Laguillo-Diego A, Kiewisz R, Marti-Gomez C, Baum D, Muller-Reichert T, Vernos I
Mol Biol Cell
. 2022 Nov;
34(1):ar1.
PMID: 36350698
Faithful chromosome segregation requires the assembly of a bipolar spindle, consisting of two antiparallel microtubule (MT) arrays having most of their minus ends focused at the spindle poles and their...
6.
Timon Perez K, Scrofani J, Vernos I
Biol Open
. 2022 Nov;
11(11).
PMID: 36318115
During mitosis, spindle assembly relies on centrosomal and acentrosomal microtubule nucleation pathways that all require the γ-Tubulin Ring Complex (γ-TuRC) and its adaptor protein NEDD1. The activity of these different...
7.
Amargant F, Pujol A, Ferrer-Vaquer A, Durban M, Martinez M, Vassena R, et al.
Mol Hum Reprod
. 2021 Sep;
27(11).
PMID: 34581808
The mechanism of conversion of the human sperm basal body to a centrosome after fertilization, and its role in supporting human early embryogenesis, has not been directly addressed so far....
8.
Gungor S, Oktay Y, Hiz S, Aranguren-Ibanez A, Kalafatcilar I, Yaramis A, et al.
iScience
. 2021 Jan;
24(1):101948.
PMID: 33458610
Microtubules help building the cytoskeleton of neurons and other cells. Several components of the gamma-tubulin (γ-tubulin) complex have been previously reported in human neurodevelopmental diseases. We describe two siblings from...
9.
Moedas C, Vernos I, Kuster S, Nowotny H, Saltelli A, Mungiu-Pippidi A, et al.
Nature
. 2019 May;
569(7757):481-484.
PMID: 31114095
No abstract available.
10.
Rosas-Salvans M, Scrofani J, Modol A, Vernos I
J Cell Sci
. 2019 May;
132(11).
PMID: 31064815
Bipolar spindle organization is essential for the faithful segregation of chromosomes during cell division. This organization relies on the collective activities of motor proteins. The minus-end-directed dynein motor complex generates...