Tom Wileman
Overview
Explore the profile of Tom Wileman including associated specialties, affiliations and a list of published articles.
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28
Citations
6703
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Recent Articles
1.
Breeze B, Connell E, Wileman T, Muller M, Vauzour D, Pontifex M
Brain Res
. 2024 Aug;
1844:149170.
PMID: 39163895
Alzheimer's Disease (AD), responsible for 62% of all dementia cases, is a progressive neurodegenerative condition that leads to cognitive dysfunction. The prevalence of AD is consistently higher in women suggesting...
2.
Gokani S, Jefferson M, Gavrilovic J, Clark A, Hildebrand F, Wileman T, et al.
PLoS One
. 2023 Aug;
18(8):e0289407.
PMID: 37531384
Background: Chronic Rhinosinusitis (CRS) affects approximately 1 in 10 UK adults and impacts quality of life quality of life significantly. Response to treatment may be driven by individual CRS endotypes...
3.
Gokani S, Espehana A, Pratas A, Luke L, Sharma E, Mattock J, et al.
Am J Rhinol Allergy
. 2023 Jul;
37(6):705-729.
PMID: 37491901
Background: Chronic rhinosinusitis (CRS) is a heterogeneous condition characterized by differing inflammatory endotypes. The identification of suitable biomarkers could enable personalized approaches to treatment selection. Objective: This study aimed to...
4.
Voronina S, Chvanov M, De Faveri F, Mayer U, Wileman T, Criddle D, et al.
Cells
. 2022 Aug;
11(16).
PMID: 36010591
Recent studies have highlighted the importance of autophagy and particularly non-canonical autophagy in the development and progression of acute pancreatitis (a frequent disease with considerable morbidity and significant mortality). An...
5.
Comparison of PCR versus PCR-Free DNA Library Preparation for Characterising the Human Faecal Virome
Hsieh S, Tariq M, Telatin A, Ansorge R, Adriaenssens E, Savva G, et al.
Viruses
. 2021 Oct;
13(10).
PMID: 34696523
The human intestinal microbiota is abundant in viruses, comprising mainly bacteriophages, occasionally outnumbering bacteria 10:1 and is termed the virome. Due to their high genetic diversity and the lack of...
6.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
7.
Modasia A, Parker A, Jones E, Stentz R, Brion A, Goldson A, et al.
Front Microbiol
. 2020 Nov;
11:575595.
PMID: 33240233
Gut microbes have critical roles in maintaining host physiology, but their effects on epithelial chemosensory enteroendocrine cells (EEC) remain unclear. We investigated the role that the ubiquitous commensal gut bacterium...
8.
Tariq M, Newberry F, Haagmans R, Booth C, Wileman T, Hoyles L, et al.
Front Microbiol
. 2020 Nov;
11:583378.
PMID: 33193224
spp. are part of the human intestinal microbiota but can under some circumstances become clinical pathogens. Phages are a potentially valuable therapeutic treatment option for many pathogens, but phage therapy...
9.
Horton R, Wileman T, Rushworth S
Curr Cancer Drug Targets
. 2020 Apr;
20(7):501-512.
PMID: 32342819
The leukaemias are a heterogeneous group of blood cancers, which together, caused 310,000 deaths in 2016. Despite significant research into their biology and therapeutics, leukaemia is predicted to account for...
10.
Jones E, Booth C, Fonseca S, Parker A, Cross K, Miquel-Clopes A, et al.
Front Microbiol
. 2020 Mar;
11:57.
PMID: 32117106
Gram-negative bacteria ubiquitously produce and release nano-size, non-replicative outer membrane vesicles (OMVs). In the gastrointestinal (GI-) tract, OMVs generated by members of the intestinal microbiota are believed to contribute to...