Wen-Xing Ding
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Explore the profile of Wen-Xing Ding including associated specialties, affiliations and a list of published articles.
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204
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14451
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Recent Articles
1.
Ma X, Wei X, Niu M, Zhang C, Peng Z, Liu W, et al.
bioRxiv
. 2025 Feb;
PMID: 39990472
Background & Aims: Mitochondrial dysfunction has been implicated in aging and various cancer development. As highly dynamic organelles, mitochondria constantly undergo fission, mediated by dynamin-related protein 1 (DRP1, gene name...
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Cao P, Chao X, Ni H, Ding W
Am J Pathol
. 2025 Jan;
PMID: 39884572
Alcohol-associated liver disease (ALD) is a significant global health concern and a leading cause of liver disease-related deaths. However, the treatment options are limited due to the lack of animal...
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5.
Chen H, Hinz K, Zhang C, Rodriguez Y, Williams S, Niu M, et al.
Biomolecules
. 2025 Jan;
14(12.
PMID: 39766244
Alcohol consumption is believed to affect Alzheimer's disease (AD) risk, but the contributing mechanisms are not well understood. A potential mediator of the proposed alcohol-AD connection is autophagy, a degradation...
6.
Ma X, Ding W
Autophagy
. 2024 Sep;
20(12):2599-2601.
PMID: 39324497
Mitochondria are crucial organelles in maintaining cellular homeostasis. They are involved in processes such as energy production, metabolism of lipids and glucose, and cell death regulation. Mitochondrial dysfunction can lead...
7.
Hinz K, Niu M, Ni H, Ding W
Livers
. 2024 Sep;
4(3):377-387.
PMID: 39301093
Acetaminophen (APAP) overdose can induce hepatocyte necrosis and acute liver failure in experimental rodents and humans. APAP is mainly metabolized via hepatic cytochrome P450 enzymes to generate the highly reactive...
8.
Yang P, Gao S, Shen J, Liu T, Lu K, Han X, et al.
Autophagy
. 2024 Aug;
21(1):178-190.
PMID: 39172027
Long-chain free fatty acids (FFAs) accumulation and oxidative toxicity is a major cause for several pathological conditions. The mechanisms underlying FFA cytotoxicity remain elusive. Here we show that palmitic acid...
9.
Subramanian S, Bu H, Chou P, Wang X, Geng H, Akhtar S, et al.
Cell Mol Gastroenterol Hepatol
. 2024 May;
18(3):101364.
PMID: 38788898
Background & Aims: Necrotizing enterocolitis (NEC) is a life-threatening disease affecting mostly the ileum of preemies. Intestinal epithelial cell (IEC) apoptosis contributes to NEC pathogenesis. However, how scattered crypt IEC...
10.
Ding W, Ma X, Kim S, Wang S, Ni H
eGastroenterology
. 2024 May;
2(2).
PMID: 38770349
Acute pancreatitis is a common inflammatory gastrointestinal disease without any successful treatment. Pancreatic exocrine acinar cells have high rates of protein synthesis to produce and secrete large amounts of digestive...