Toivo Maimets
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Explore the profile of Toivo Maimets including associated specialties, affiliations and a list of published articles.
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31
Citations
322
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Recent Articles
1.
Stukas D, Zievyte I, Ivanauskiene S, Karvelyte G, Jasukaitiene A, Bartkeviciene A, et al.
Biochem Pharmacol
. 2025 Feb;
233:116798.
PMID: 39947435
Pancreatic cancer (PC) presents a significant challenge in treatment efficacy due to late-stage diagnosis and chemoresistance. The effects of the combination of a selective small-molecule AHR inhibitor and gemcitabine treatmenteffectiveness...
2.
Kannen V, Rasmussen M, Das S, Giuliana P, Izzati F, Choksi H, et al.
Front Immunol
. 2025 Jan;
15:1513595.
PMID: 39867896
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal forms of cancer, and despite low incidence rates, it remains the sixth leading cause of cancer related deaths worldwide....
3.
Bobrovs R, Terentjeva S, Olafsen N, Dambrauskas Z, Gulbinas A, Maimets T, et al.
RSC Med Chem
. 2024 Sep;
PMID: 39246744
The aryl hydrocarbon receptor (AHR) is a versatile ligand-dependent transcription factor involved in diverse biological processes, from metabolic adaptations to immune system regulation. Recognising its pivotal role in cancer immunology,...
4.
Bartkeviciene A, Jasukaitiene A, Zievyte I, Stukas D, Ivanauskiene S, Urboniene D, et al.
Cancers (Basel)
. 2023 Sep;
15(18).
PMID: 37760608
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), has an immune suppressive environment that allows tumour cells to evade the immune system. The aryl-hydrocarbon receptor (AHR) is a transcription factor that...
5.
Stukas D, Jasukaitiene A, Bartkeviciene A, Matthews J, Maimets T, Teino I, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37685961
The aryl hydrocarbon receptor (AHR) is a transcription factor that is commonly upregulated in pancreatic ductal adenocarcinoma (PDAC). AHR hinders the shuttling of human antigen R (ELAVL1) from the nucleus...
6.
Ervin E, Pooga M, Maimets T
Methods Mol Biol
. 2021 Nov;
2383:579-585.
PMID: 34766315
The unique properties of human embryonic stem (hES) cells render them invaluable for many scientific and clinical endeavors. Wider application of hES cells requires a comprehensive understanding of their biology...
7.
Klepinina L, Klepinin A, Truu L, Chekulayev V, Vija H, Kuus K, et al.
PLoS One
. 2021 Jan;
16(1):e0245348.
PMID: 33471801
The ability of butyrate to promote differentiation of cancer cells has important implication for colorectal cancer (CRC) prevention and therapy. In this study, we examined the effect of sodium butyrate...
8.
Teino I, Matvere A, Pook M, Varik I, Pajusaar L, Uudekull K, et al.
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33260776
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor, which mediates the effects of a variety of environmental stimuli in multiple tissues. Recent advances in AHR biology have underlined its...
9.
Hensen K, Pook M, Sikut A, Org T, Maimets T, Salumets A, et al.
Mol Cell Endocrinol
. 2020 Apr;
510:110816.
PMID: 32294491
Human granulosa cells acquired as leftover from IVF treatment can be used to study infertility problems and are a valuable tool in the research of follicle maturation and ovulation. There...
10.
Matvere A, Teino I, Varik I, Kuuse S, Tiido T, Kristjuhan A, et al.
Int J Mol Sci
. 2019 Jun;
20(12).
PMID: 31234584
The aryl hydrocarbon receptor (Ahr) is a ligand-activated transcription factor primarily known for its toxicological functions. Recent studies have established its importance in many physiological processes including female reproduction, although...