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Tohru Tsujimura

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Articles 123
Citations 7695
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Recent Articles
1.
Uehata T, Yamada S, Ori D, Vandenbon A, Giladi A, Jelinski A, et al.
Blood . 2023 Nov; 143(3):243-257. PMID: 37922454
Regulation of lineage biases in hematopoietic stem and progenitor cells (HSPCs) is pivotal for balanced hematopoietic output. However, little is known about the mechanism behind lineage choice in HSPCs. Here,...
2.
Sato T, Akao K, Sato A, Tsujimura T, Mukai S, Sekido Y
Cancer Med . 2023 May; 12(12):13586-13598. PMID: 37165917
Background: Mesothelioma is a neoplastic disease associated with asbestos exposure. It is highly malignant and has a poor prognosis; thus, early detection is desirable. Recent whole-genome analysis has revealed that...
3.
Sa-Ngiamwibool P, Hamasaki M, Kinoshita Y, Matsumoto S, Sato A, Tsujimura T, et al.
Lung Cancer . 2022 Nov; 175:27-35. PMID: 36442384
Objectives: BAP1, CDKN2A, and NF2 are the most frequently altered genes in pleural mesotheliomas (PM). Discriminating PM from benign mesothelial proliferation (BMP) is sometimes challenging; it is well established that...
4.
Hashimoto M, Yuki M, Kitajima K, Fukuda A, Nakamichi T, Nakamura A, et al.
Cancers (Basel) . 2022 Sep; 14(18). PMID: 36139517
To investigate the incidence and risk factors of chest wall metastasis (CWM) at biopsy sites in patients with malignant pleural mesothelioma (MPM). This retrospective cohort study was conducted in 262...
5.
Yaku A, Inagaki T, Asano R, Okazawa M, Mori H, Sato A, et al.
Circulation . 2022 Aug; 146(13):1006-1022. PMID: 35997026
Background: Pulmonary arterial hypertension (PAH) is a type of pulmonary hypertension (PH) characterized by obliterative pulmonary vascular remodeling, resulting in right-sided heart failure. Although the pathogenesis of PAH is not...
6.
Sa-Ngiamwibool P, Hamasaki M, Kinoshita Y, Matsumoto S, Sato A, Tsujimura T, et al.
Ann Diagn Pathol . 2022 Jul; 60:152004. PMID: 35797798
Aim: Genomic-based ancillary assays including immunohistochemistry (IHC) for BRCA-1 associated protein-1 (BAP1) and methylthioadenosine phosphorylase (MTAP), and fluorescence in situ hybridization (FISH) for CDKN2A are effective for differentiating pleural mesothelioma...
7.
Tse K, Vandenbon A, Cui X, Mino T, Uehata T, Yasuda K, et al.
Sci Transl Med . 2022 May; 14(644):eabo2137. PMID: 35544597
Regnase-1 is an ribonuclease that plays essential roles in restricting inflammation through degrading messenger RNAs (mRNAs) involved in immune reactions via the recognition of stem-loop (SL) structures in the 3'...
8.
Oyama Y, Hamasaki M, Matsumoto S, Sato A, Tsujimura T, Nabeshima K
Oncol Lett . 2021 Oct; 22(6):813. PMID: 34671427
Homozygous deletion (homo-d) of the cyclin-dependent kinase inhibitor 2A () gene is frequently found in malignant pleural mesothelioma (MPM). Fluorescence hybridization (FISH) is commonly used to detect chromosomal deletion, and...
9.
Kinoshita Y, Hamasaki M, Matsumoto S, Yoshimura M, Sato A, Tsujimura T, et al.
Cancer Cytopathol . 2021 Jan; 129(7):526-536. PMID: 33493384
Background: Malignant pleural mesothelioma (MPM) is characterized by mutations in several genes, including cyclin-dependent kinase-inhibitor 2A/p16 in the 9p21 locus, BRCA1-associated protein 1 (BAP1), and neurofibromatosis type 2 (NF2) in...
10.
Onizawa H, Kato H, Kimura H, Kudo T, Soda N, Shimizu S, et al.
Int Immunol . 2020 Nov; 33(4):225-240. PMID: 33165593
MDA5 is a cytoplasmic sensor of viral RNA, triggering type I interferon (IFN-I) production. Constitutively active MDA5 has been linked to autoimmune diseases such as systemic lupus erythematosus, Singleton-Merten syndrome...