Todd Link
Overview
Explore the profile of Todd Link including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
5
Citations
355
Followers
0
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Recent Articles
1.
Brosey C, Houl J, Katsonis P, Balapiti-Modarage L, Bommagani S, Arvai A, et al.
Prog Biophys Mol Biol
. 2021 Feb;
163:171-186.
PMID: 33636189
Arrival of the novel SARS-CoV-2 has launched a worldwide effort to identify both pre-approved and novel therapeutics targeting the viral proteome, highlighting the urgent need for efficient drug discovery strategies....
2.
Chan W, Horvath T, Tan L, Link T, Harutyunyan K, Pontikos M, et al.
Mol Cancer Ther
. 2019 Jun;
18(9):1587-1592.
PMID: 31209181
We and others have reported that the anticancer activity of L-asparaginase (ASNase) against asparagine synthetase (ASNS)-positive cell types requires ASNase glutaminase activity, whereas anticancer activity against ASNS-negative cell types does...
3.
Ishizawa J, Zarabi S, Davis R, Halgas O, Nii T, Jitkova Y, et al.
Cancer Cell
. 2019 May;
35(5):721-737.e9.
PMID: 31056398
The mitochondrial caseinolytic protease P (ClpP) plays a central role in mitochondrial protein quality control by degrading misfolded proteins. Using genetic and chemical approaches, we showed that hyperactivation of the...
4.
Sakamaki T, Casimiro M, Ju X, Quong A, Katiyar S, Liu M, et al.
Mol Cell Biol
. 2006 Jul;
26(14):5449-69.
PMID: 16809779
The cyclin D1 gene encodes a regulatory subunit of the holoenzyme that phosphorylates and inactivates the pRb tumor suppressor to promote nuclear DNA synthesis. cyclin D1 is overexpressed in human...
5.
Van Lanen S, Kinzie S, Matthieu S, Link T, Culp J, Iwata-Reuyl D
J Biol Chem
. 2003 Jan;
278(12):10491-9.
PMID: 12533518
The enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase catalyzes the penultimate step in the biosynthesis of the hypermodified tRNA nucleoside queuosine (Q), an unprecedented ribosyl transfer from the cofactor S-adenosylmethionine (AdoMet) to a modified-tRNA...