Todd Kirchgessner
Overview
Explore the profile of Todd Kirchgessner including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
1385
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Civelek M, Wu Y, Pan C, Raulerson C, Ko A, He A, et al.
Am J Hum Genet
. 2017 Mar;
100(3):428-443.
PMID: 28257690
Subcutaneous adipose tissue stores excess lipids and maintains energy balance. We performed expression quantitative trait locus (eQTL) analyses by using abdominal subcutaneous adipose tissue of 770 extensively phenotyped participants of...
2.
Kick E, Busch B, Martin R, Stevens W, Bollu V, Xie Y, et al.
ACS Med Chem Lett
. 2016 Dec;
7(12):1207-1212.
PMID: 27994765
Introducing a uniquely substituted phenyl sulfone into a series of biphenyl imidazole liver X receptor (LXR) agonists afforded a dramatic potency improvement for induction of ATP binding cassette transporters, ABCA1...
3.
Bennett B, Davis R, Civelek M, Orozco L, Wu J, Qi H, et al.
PLoS Genet
. 2016 Mar;
12(3):e1005913.
PMID: 26934746
No abstract available.
4.
Bennett B, Davis R, Civelek M, Orozco L, Wu J, Qi H, et al.
PLoS Genet
. 2015 Dec;
11(12):e1005711.
PMID: 26694027
Common forms of atherosclerosis involve multiple genetic and environmental factors. While human genome-wide association studies have identified numerous loci contributing to coronary artery disease and its risk factors, these studies...
5.
Hui S, Parks B, Org E, Norheim F, Che N, Pan C, et al.
Elife
. 2015 Jun;
4:e05607.
PMID: 26067236
To identify genetic and environmental factors contributing to the pathogenesis of non-alcoholic fatty liver disease, we examined liver steatosis and related clinical and molecular traits in more than 100 unique...
6.
Kick E, Martin R, Xie Y, Flatt B, Schweiger E, Wang T, et al.
Bioorg Med Chem Lett
. 2014 Dec;
25(2):372-7.
PMID: 25435151
A series of biaryl pyrazole and imidazole Liver X Receptor (LXR) partial agonists has been synthesized displaying LXRβ selectivity. The LXRβ selective partial agonist 18 was identified with potent induction...
7.
Ghazalpour A, Bennett B, Shih D, Che N, Orozco L, Pan C, et al.
Mol Syst Biol
. 2014 May;
10:730.
PMID: 24860088
We profiled and analyzed 283 metabolites representing eight major classes of molecules including Lipids, Carbohydrates, Amino Acids, Peptides, Xenobiotics, Vitamins and Cofactors, Energy Metabolism, and Nucleotides in mouse liver of...
8.
Parks B, Nam E, Org E, Kostem E, Norheim F, Hui S, et al.
Cell Metab
. 2013 Jan;
17(1):141-52.
PMID: 23312289
Obesity is a highly heritable disease driven by complex interactions between genetic and environmental factors. Human genome-wide association studies (GWAS) have identified a number of loci contributing to obesity; however,...
9.
Orozco L, Bennett B, Farber C, Ghazalpour A, Pan C, Che N, et al.
Cell
. 2012 Oct;
151(3):658-70.
PMID: 23101632
Many common diseases have an important inflammatory component mediated in part by macrophages. Here we used a systems genetics strategy to examine the role of common genetic variation in macrophage...
10.
Ghazalpour A, Rau C, Farber C, Bennett B, Orozco L, van Nas A, et al.
Mamm Genome
. 2012 Aug;
23(9-10):680-92.
PMID: 22892838
We have developed an association-based approach using classical inbred strains of mice in which we correct for population structure, which is very extensive in mice, using an efficient mixed-model algorithm....