Todd E Fox
Overview
Explore the profile of Todd E Fox including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
72
Citations
1564
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Khokhlatchev A, Sharma A, Deering T, Shaw J, Costa-Pinheiro P, Golla U, et al.
FASEB J
. 2022 Sep;
36(10):e22514.
PMID: 36106439
Despite several new therapeutic options for acute myeloid leukemia (AML), disease relapse remains a significant challenge. We have previously demonstrated that augmenting ceramides can counter various drug-resistance mechanisms, leading to...
12.
Ung J, Tan S, Fox T, Shaw J, Vass L, Costa-Pinheiro P, et al.
Blood Rev
. 2022 Apr;
55:100950.
PMID: 35487785
Acute myeloid leukemia (AML) is an aggressive, heterogenous malignancy characterized by clonal expansion of bone marrow-derived myeloid progenitor cells. While our current understanding of the molecular and genomic landscape of...
13.
DiPasquale M, Deering T, Desai D, Sharma A, Amin S, Fox T, et al.
Chem Phys Lipids
. 2022 Apr;
245:105205.
PMID: 35483419
Ceramides and diacylglycerols are groups of lipids capable of nucleating and stabilizing ordered lipid domains, structures that have been implicated in a range of biological processes. Previous studies have used...
14.
Fisher-Wellman K, Hagen J, Kassai M, Kao L, Nelson M, McLaughlin K, et al.
FASEB J
. 2021 Dec;
36(1):e22094.
PMID: 34888943
Modifications in sphingolipid (SL) metabolism and mitochondrial bioenergetics are key factors implicated in cancer cell response to chemotherapy, including chemotherapy resistance. In the present work, we utilized acute myeloid leukemia...
15.
Costa-Pinheiro P, Heher A, Raymond M, Jividen K, Shaw J, Paschal B, et al.
iScience
. 2020 Dec;
23(12):101855.
PMID: 33313495
Anti-androgens are a common therapy in prostate cancer (PCa) targeting androgen receptor (AR) signaling. However, these therapies fail due to selection of highly aggressive AR-negative cancer cells that have no...
16.
Shaw J, Boyer T, Venner E, Beck P, Slamowitz T, Caste T, et al.
Mol Cancer Ther
. 2020 Oct;
19(12):2621-2633.
PMID: 33087509
Therapies for head and neck squamous cell carcinoma (HNSCC) are, at best, moderately effective, underscoring the need for new therapeutic strategies. Ceramide treatment leads to cell death as a consequence...
17.
Patterson L, Allen J, Posey I, Shaw J, Costa-Pinheiro P, Walker S, et al.
FASEB J
. 2020 Oct;
34(12):15922-15945.
PMID: 33047400
Enterotoxigenic Bacteroides fragilis (ETBF) is a commensal bacterium of great importance to human health due to its ability to induce colitis and cause colon tumor formation in mice through the...
18.
Keppley L, Walker S, Gademsey A, Smith J, Keller S, Kester M, et al.
FASEB J
. 2020 Sep;
34(11):15314-15326.
PMID: 32959931
Lipid perturbations contribute to detrimental outcomes in obesity. We previously demonstrated that nervonic acid, a C24:1 ω-9 fatty acid, predominantly acylated to sphingolipids, including ceramides, are selectively reduced in a...
19.
Olson K, Moosic K, Jones M, Larkin P, Olson T, Toro M, et al.
Cancer Med
. 2020 Jul;
9(18):6533-6549.
PMID: 32710512
Large granular lymphocyte (LGL) leukemia is a rare hematological disorder with expansion of the T-cell or natural killer (NK) cell lineage. Signal transducer and activator of transcription 3 (STAT3) exhibits...
20.
Bories G, Yeudall S, Serbulea V, Fox T, Isakson B, Leitinger N
Blood
. 2020 Jun;
136(13):1535-1548.
PMID: 32556090
Heme is an essential cofactor for numerous cellular functions, but release of free heme during hemolysis results in oxidative tissue damage, vascular dysfunction, and inflammation. Macrophages play a key protective...