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Toby Lawrence

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Articles 74
Citations 11606
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Recent Articles
1.
Wang Y, Dowling S, Rodriguez V, Maciuch J, Mayer M, Therron T, et al.
bioRxiv . 2025 Mar; PMID: 40060446
Macrophages are a pivotal cell type within the synovial lining and sub-lining of the joint, playing a crucial role in maintaining homeostasis of synovium. Although fate-mapping techniques have been employed...
2.
Zhou B, Liu Y, Ma H, Zhang B, Lu B, Li S, et al.
Biochim Biophys Acta Mol Basis Dis . 2024 Nov; 1871(2):167577. PMID: 39566590
Monocyte-to-macrophage differentiation and subsequent foam cell formation are key processes that contribute to plaque build-up during the progression of atherosclerotic lesions. Palmitoylation enzymes are known to play pivotal roles in...
3.
Alraies Z, Rivera C, Delgado M, Sanseau D, Maurin M, Amadio R, et al.
Nat Immunol . 2024 Jun; 25(7):1193-1206. PMID: 38834865
Immune cells experience large cell shape changes during environmental patrolling because of the physical constraints that they encounter while migrating through tissues. These cells can adapt to such deformation events...
4.
Anstee J, Feehan K, Opzoomer J, Dean I, Muller H, Bahri M, et al.
Dev Cell . 2023 Jul; 58(17):1548-1561.e10. PMID: 37442140
Tumor-associated macrophages (TAMs) are a heterogeneous population of cells that facilitate cancer progression. However, our knowledge of the niches of individual TAM subsets and their development and function remain incomplete....
5.
Anderson A, Robinson A, Giddens E, Hartshorn B, Allan E, Rowe C, et al.
Drug Alcohol Depend . 2023 Apr; 246:109846. PMID: 37004463
Background: Deficits in executive function are common in methamphetamine use disorder (MUD), likely contributing to difficulties in sustained treatment success. Cognitive remediation interventions are designed to treat such deficits but...
6.
Rebejac J, Eme-Scolan E, Paroutaud L, Kharbouche S, Teleman M, Spinelli L, et al.
Immunity . 2022 Nov; 55(11):2103-2117.e10. PMID: 36323311
The surface of the central nervous system (CNS) is protected by the meninges, which contain a dense network of meningeal macrophages (MMs). Here, we examined the role of tissue-resident MM...
7.
Gu Y, Lawrence T, Mohamed R, Liang Y, Yahaya B
Front Immunol . 2022 Oct; 13:923235. PMID: 36211428
Pulmonary fibrosis is an irreversible and progressive disease affecting the lungs, and the etiology remains poorly understood. This disease can be lethal and currently has no specific clinical therapeutic regimen....
8.
Zhang L, Feng X, Shen Y, Wang Y, Liu Z, Ma Y, et al.
Immunol Cell Biol . 2022 Jul; 100(9):691-704. PMID: 35849045
Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) is an efficient tool for establishing genetic models including cellular models, and has facilitated unprecedented advancements in biomedical research. In both...
9.
Guillot J, Dominici C, Lucchesi A, Nguyen H, Puget A, Hocine M, et al.
Nat Commun . 2022 Apr; 13(1):1985. PMID: 35418199
Neuronal nerve processes in the tumor microenvironment were highlighted recently. However, the origin of intra-tumoral nerves remains poorly known, in part because of technical difficulties in tracing nerve fibers via...
10.
Benoit-Lizon I, Jacquin E, Rivera Vargas T, Richard C, Roussey A, Dal Zuffo L, et al.
J Immunother Cancer . 2022 Jan; 10(1). PMID: 35091453
Background: While stimulator of interferon genes (STING) activation in innate immune cells of the tumor microenvironment can result in CD8 T cell-dependent antitumor immunity, whether STING signaling affects CD4 T-cell...