Ting-Fen Tsai
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Explore the profile of Ting-Fen Tsai including associated specialties, affiliations and a list of published articles.
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92
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4353
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Recent Articles
1.
Wu I, Liao Y, Tsai T, Lin C, Shen Z, Chan Y, et al.
Gut Microbes
. 2025 Mar;
17(1):2473506.
PMID: 40050256
Diabetic kidney disease (DKD) is a serious healthcare dilemma. Nonetheless, the interplay between the functional capacity of gut microbiota and their host remains elusive for DKD. This study aims to...
2.
Yeh C, Tsai T, Chen C, Chou Y, Mao C, Su T, et al.
Comput Struct Biotechnol J
. 2025 Jan;
27:278-286.
PMID: 39881827
An AI-assisted algorithm has been developed to improve the detection of significant coronary artery disease (CAD) in high-risk individuals who have normal electrocardiograms (ECGs). This retrospective study analyzed ECGs from...
3.
Transcriptomic predictors of rapid progression from mild cognitive impairment to Alzheimer's disease
Huang Y, Tsai T, Shen Z, Chan Y, Tu C, Tung C, et al.
Alzheimers Res Ther
. 2025 Jan;
17(1):3.
PMID: 39754267
Background: Effective treatment for Alzheimer's disease (AD) remains an unmet need. Thus, identifying patients with mild cognitive impairment (MCI) who are at high-risk of progressing to AD is crucial for...
4.
Hung H, Lin J, Teng Y, Kao C, Wang P, Soong B, et al.
J Pathol
. 2024 Nov;
265(1):57-68.
PMID: 39562497
Spinocerebellar ataxia type 22 (SCA22) caused by KCND3 mutations is an autosomal dominant disorder. We established a mouse model carrying the Kcnd3 F227del mutation to study the molecular pathogenesis. Four...
5.
Chen H, Wang Y, Lei C, Guo Y, Tang M, Tsai T, et al.
Aging Dis
. 2024 Sep;
PMID: 39226169
Age-related hearing loss (ARHL) is a disease that impacts human quality of life and contributes to the progression of other neuronal problems. Various stressors induce an increase in free radicals,...
6.
Liiv M, Vaarmann A, Safiulina D, Choubey V, Gupta R, Kuum M, et al.
Nat Commun
. 2024 Jul;
15(1):6143.
PMID: 39034309
Wolfram syndrome is a rare genetic disease caused by mutations in the WFS1 or CISD2 gene. A primary defect in Wolfram syndrome involves poor ER Ca handling, but how this...
7.
Shen Z, Chang C, Yeh C, Lu C, Hung H, Wang T, et al.
J Biomed Sci
. 2024 Jan;
31(1):15.
PMID: 38263133
Background: CDGSH iron-sulfur domain-containing protein 2 (CISD2), a pro-longevity gene, mediates healthspan in mammals. CISD2 is down-regulated during aging. Furthermore, a persistently high level of CISD2 promotes longevity and ameliorates...
8.
Yao C, Shen Z, Rajan Y, Huang Y, Lin C, Song J, et al.
Eur J Med Chem
. 2023 Jul;
258:115583.
PMID: 37393792
Down-regulation of Cisd2 in the liver has been implicated in the development of nonalcoholic fatty liver disease (NAFLD) and increasing the level of Cisd2 is therefore a potential therapeutic approach...
9.
Sun C, Lee S, Chen L, Lai C, Shen Z, Chen N, et al.
Cell Signal
. 2023 Jun;
109:110755.
PMID: 37315750
Chronic epithelial defects of the cornea, which are usually associated with severe dry eye disease, diabetes mellitus, chemical injuries or neurotrophic keratitis, as well as aging, are an unmet clinical...
10.
Huang C, Lee W, Huang Y, Tsai T, Chen L, Lin C
J Gerontol A Biol Sci Med Sci
. 2023 May;
78(10):1799-1808.
PMID: 37148322
The aging process is complicated and involves diverse organ dysfunction; furthermore, the biomarkers that are able to reflect biological aging are eagerly sought after to monitor the system-wide decline associated...