Timothy N C Wells
Overview
Explore the profile of Timothy N C Wells including associated specialties, affiliations and a list of published articles.
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Articles
72
Citations
3331
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Recent Articles
1.
El Gaaloul M, Tchouatieu A, Kayentao K, Campo B, Buffet B, Ramachandruni H, et al.
Malar J
. 2024 Nov;
23(1):363.
PMID: 39614327
No abstract available.
2.
El Gaaloul M, Tchouatieu A, Kayentao K, Campo B, Buffet B, Ramachandruni H, et al.
Malar J
. 2024 Oct;
23(1):315.
PMID: 39425110
Malaria is preventable, but the burden of disease remains high with over 249 million cases and 608,000 deaths reported in 2022. Historically, the most important protective interventions have been vector...
3.
Abla N, Almond L, Bonner J, Richardson N, Wells T, Mohrle J
Clin Transl Sci
. 2024 Jul;
17(7):e13865.
PMID: 39020517
The urgent need for safe, efficacious, and accessible drug treatments to treat coronavirus disease 2019 (COVID-19) prompted a global effort to evaluate drug repurposing opportunities. Pyronaridine and amodiaquine are both...
4.
Policastro L, Dolci I, Godoy A, Silva Junior J, Ruiz U, Santos I, et al.
Viruses
. 2022 Jul;
14(7).
PMID: 35891332
Chikungunya virus (CHIKV) is the causative agent of chikungunya fever, a disabling disease that can cause long-term severe arthritis. Since the last large CHIKV outbreak in 2015, the reemergence of...
5.
Jonsdottir H, Siegrist D, Julien T, Padey B, Bouveret M, Terrier O, et al.
Biomed Pharmacother
. 2022 Jun;
150:113058.
PMID: 35658229
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide pandemic with unprecedented economic and societal impact. Currently, several vaccines are available and multitudes of antiviral treatments have...
6.
Samby K, Besson D, Dutta A, Patra B, Doy A, Glossop P, et al.
ACS Infect Dis
. 2022 Mar;
8(4):713-720.
PMID: 35286809
The current Covid-19 pandemic has underlined the need for a more coordinated and forward-looking investment in the search for new medicines targeting emerging health care threats. Repositioning currently approved drugs...
7.
Belardinelli J, Verma D, Li W, Avanzi C, Wiersma C, Williams J, et al.
Sci Transl Med
. 2022 Feb;
14(633):eabj3860.
PMID: 35196022
A search for alternative treatments led to our interest in the two-component regulator DosRS, which, in , is required for the bacterium to establish a state of nonreplicating, drug-tolerant persistence...
8.
Adoke Y, Zoleko-Manego R, Ouoba S, Tiono A, Kaguthi G, Bonzela J, et al.
Malar J
. 2021 May;
20(1):222.
PMID: 34011358
Background: For uncomplicated Plasmodium falciparum malaria, highly efficacious single-dose treatments are expected to increase compliance and improve treatment outcomes, and thereby may slow the development of resistance. The efficacy and...
9.
Duffey M, Blasco B, Burrows J, Wells T, Fidock D, Leroy D
Trends Parasitol
. 2021 May;
37(8):709-721.
PMID: 34001441
Strategies to counteract or prevent emerging drug resistance are crucial for the design of next-generation antimalarials. In the past, resistant parasites were generally identified following treatment failures in patients, and...
10.
Lynham S, Grundland Freile F, Puri N, OReilly N, Mitchell G, Wells T, et al.
Sci Rep
. 2021 Apr;
11(1):7740.
PMID: 33833368
The discovery of compounds and proteins from plants has greatly contributed to modern medicine. Vernonia amygdalina Del. (Compositae) is used by humans and primates for a variety of conditions including...