Timothy E A Peto
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Explore the profile of Timothy E A Peto including associated specialties, affiliations and a list of published articles.
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54
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2599
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Recent Articles
1.
Carter J, Walker T, Walker A, Whitfield M, Morlock G, Lynch C, et al.
JAC Antimicrob Resist
. 2024 Mar;
6(2):dlae037.
PMID: 38500518
Background: Pyrazinamide is one of four first-line antibiotics used to treat tuberculosis; however, antibiotic susceptibility testing for pyrazinamide is challenging. Resistance to pyrazinamide is primarily driven by genetic variation in...
2.
Davies T, Swann J, Sheppard A, Pickford H, Lipworth S, AbuOun M, et al.
Microb Genom
. 2023 Dec;
9(12).
PMID: 38100178
Several bioinformatics genotyping algorithms are now commonly used to characterize antimicrobial resistance (AMR) gene profiles in whole-genome sequencing (WGS) data, with a view to understanding AMR epidemiology and developing resistance...
3.
Llewelyn M, Budgell E, Laskawiec-Szkonter M, L A Cross E, Alexander R, Bond S, et al.
Lancet Infect Dis
. 2022 Oct;
23(2):207-221.
PMID: 36206793
Background: Strategies to reduce antibiotic overuse in hospitals depend on prescribers taking decisions to stop unnecessary antibiotic use. There is scarce evidence for how to support these decisions. We evaluated...
4.
Fowler P, Wright C, Spiers H, Zhu T, Baeten E, Hoosdally S, et al.
Elife
. 2022 May;
11.
PMID: 35588296
Tuberculosis is a respiratory disease that is treatable with antibiotics. An increasing prevalence of resistance means that to ensure a good treatment outcome it is desirable to test the susceptibility...
5.
Walker T, Choisy M, Dedicoat M, Drennan P, Wyllie D, Yang-Turner F, et al.
Lancet Reg Health Eur
. 2022 Mar;
17:100361.
PMID: 35345560
Background: Over 10-years of whole-genome sequencing (WGS) of in Birmingham presents an opportunity to explore epidemiological trends and risk factors for transmission in new detail. Methods: Between 1st January 2009...
6.
Matlock W, Lipworth S, Constantinides B, Peto T, Walker A, Crook D, et al.
Microb Genom
. 2021 Sep;
7(9).
PMID: 34559044
Analysing the flanking sequences surrounding genes of interest is often highly relevant to understanding the role of mobile genetic elements (MGEs) in horizontal gene transfer, particular for antimicrobial-resistance genes. Here,...
7.
Lipworth S, Vihta K, Chau K, Barker L, George S, Kavanagh J, et al.
Genome Med
. 2021 Sep;
13(1):144.
PMID: 34479643
Background: The incidence of Gram-negative bloodstream infections (BSIs), predominantly caused by Escherichia coli and Klebsiella species, continues to increase; however, the causes of this are unclear and effective interventions are...
8.
Yang Y, Walker T, Kouchaki S, Wang C, Peto T, Crook D, et al.
Brief Bioinform
. 2021 Aug;
22(6).
PMID: 34414415
Antimicrobial resistance (AMR) poses a threat to global public health. To mitigate the impacts of AMR, it is important to identify the molecular mechanisms of AMR and thereby determine optimal...
9.
Peto L, Rodger G, Carter D, Osman K, Yavuz M, Johnson K, et al.
J Clin Microbiol
. 2021 Mar;
59(6).
PMID: 33782112
LamPORE is a novel diagnostic platform for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA combining loop-mediated isothermal amplification with nanopore sequencing, which could potentially be used...
10.
Lythgoe K, Hall M, Ferretti L, de Cesare M, MacIntyre-Cockett G, Trebes A, et al.
Science
. 2021 Mar;
372(6539).
PMID: 33688063
Extensive global sampling and sequencing of the pandemic virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have enabled researchers to monitor its spread and to identify concerning new variants. Two...