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Timothy Craggs

Explore the profile of Timothy Craggs including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 58
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Recent Articles
1.
Evans G, Craggs T, Kapanidis A
J Mol Biol . 2021 Dec; 434(2):167410. PMID: 34929202
DNA polymerases maintain genomic integrity by copying DNA with high fidelity, part of which relies on the polymerase fingers opening-closing transition, a series of conformational changes during the DNA synthesis...
2.
Fisher G, Pastrana C, Higman V, Koh A, Taylor J, Butterer A, et al.
Elife . 2017 Dec; 6. PMID: 29244022
The ParB protein forms DNA bridging interactions around to condense DNA and earmark the bacterial chromosome for segregation. The molecular mechanism underlying the formation of these ParB networks is unclear....
3.
Evans G, Hohlbein J, Craggs T, Aigrain L, Kapanidis A
Nucleic Acids Res . 2015 May; 43(12):5998-6008. PMID: 26013816
DNA polymerases maintain genomic integrity by copying DNA with high fidelity. A conformational change important for fidelity is the motion of the polymerase fingers subdomain from an open to a...