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Timothy C Thompson

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Articles 119
Citations 3065
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Recent Articles
1.
Timme T, Goltsov A, Tahir S, Li L, Wang J, Ren C, et al.
Oncogene . 2025 Feb; 44(8):561. PMID: 39920290
No abstract available.
2.
Rao X, Tseng M, Zheng X, Dong Y, Jamshidi-Parsian A, Thompson T, et al.
Cancer Gene Ther . 2024 Dec; 32(1):147. PMID: 39633010
No abstract available.
3.
Gregg J, Newcomb L, Wu R, Dennison J, Davis J, Pettaway C, et al.
Biomark Res . 2024 Nov; 12(1):134. PMID: 39522029
Background: We previously reported that increases in circulating sphingolipids are associated with elevated risk of biopsy Gleason grade group (GG) upgrading in men on Active Surveillance (AS) for prostate cancer....
4.
Wolfe A, Cui T, Baie S, Corrales-Guerrero S, Webb A, Castro-Aceituno V, et al.
Sci Adv . 2024 Mar; 10(9):eadj3551. PMID: 38427741
Pancreatic ductal adenocarcinoma (PDAC) is characterized by its nutrient-scavenging ability, crucial for tumor progression. Here, we investigated the roles of caveolae-mediated endocytosis (CME) in PDAC progression. Analysis of patient data...
5.
Geng C, Zhang M, Manyam G, Vykoukal J, Fahrmann J, Peng S, et al.
Clin Cancer Res . 2023 Aug; 29(21):4464-4478. PMID: 37581614
Purpose: Speckle-type POZ protein (SPOP) is important in DNA damage response (DDR) and maintenance of genomic stability. Somatic heterozygous missense mutations in the SPOP substrate-binding cleft are found in up...
6.
Linares J, Cid-Diaz T, Duran A, Osrodek M, Martinez-Ordonez A, Reina-Campos M, et al.
Cell Rep . 2022 May; 39(6):110792. PMID: 35545049
Reduced p62 levels are associated with the induction of the cancer-associated fibroblast (CAF) phenotype, which promotes tumorigenesis in vitro and in vivo through inflammation and metabolic reprogramming. However, how p62...
7.
Yanagisawa N, Satoh T, Tabata K, Tsumura H, Nasu Y, Watanabe M, et al.
Asian J Urol . 2021 Aug; 8(3):280-288. PMID: 34401335
Objective: Cytopathic effects and local immune response were analyzed histologically in prostatic cancer (PCa) with herpes simplex virus-thymidine kinase (HSV-)/ganciclovir (GCV) gene therapy (GT). Methods: Four high-risk PCa patients who...
8.
Tang Z, Pilie P, Geng C, Manyam G, Yang G, Park S, et al.
Clin Cancer Res . 2021 Jun; 27(17):4898-4909. PMID: 34168048
Purpose: Despite significant benefit for other cancer subtypes, immune checkpoint blockade (ICB) therapy has not yet been shown to significantly improve outcomes for men with castration-resistant prostate cancer (CRPC). Prior...
9.
Wu C, Peng S, Pilie P, Geng C, Park S, Manyam G, et al.
Mol Cancer Ther . 2021 Jun; 20(9):1680-1691. PMID: 34158347
We analyzed the efficacy and mechanistic interactions of PARP inhibition (PARPi; olaparib) and CDK4/6 inhibition (CDK4/6i; palbociclib or abemaciclib) combination therapy in castration-resistant prostate cancer (CRPC) and neuroendocrine prostate cancer...
10.
Ranasinghe W, Shapiro D, Zhang M, Bathala T, Navone N, Thompson T, et al.
Nat Rev Urol . 2021 Apr; 18(6):337-358. PMID: 33824525
Ductal adenocarcinoma (DAC) is the most common variant histological subtype of prostate carcinoma and has an aggressive clinical course. DAC is usually characterized and treated as high-risk prostatic acinar adenocarcinoma...