Timothy A Donlon
Overview
Explore the profile of Timothy A Donlon including associated specialties, affiliations and a list of published articles.
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48
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1343
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Recent Articles
1.
Association of alcohol with lung cancer risk in men with different growth hormone receptor genotypes
Chen R, Donlon T, Morris B, Allsopp R, Willcox B, Masaki K
Lung Cancer
. 2024 Nov;
198:107971.
PMID: 39541775
Objective: To test whether genetic variants of the growth hormone receptor gene (GHR) modulate the effect of lifestyle variables on lung cancer (LC) risk. Materials And Methods: This population-based cohort...
2.
Chen R, Morris B, Donlon T, Nakagawa K, Allsopp R, Willcox B, et al.
J Gerontol A Biol Sci Med Sci
. 2024 Nov;
79(12).
PMID: 39497655
Background: This study tested whether the carriage of the longevity-associated G-allele of FOXO3 SNP rs2802292 (TG/GG) protects against incident coronary artery disease (CAD) in men with hypertension. Methods: Subjects were...
3.
Noureddine S, Schneider A, Strader S, Zhu X, Dhahbi J, Allsopp R, et al.
Aging Cell
. 2024 May;
23(8):e14191.
PMID: 38751007
Nonagenarians and centenarians serve as successful examples of aging and extended longevity, showcasing robust regulation of biological mechanisms and homeostasis. Given that human longevity is a complex field of study...
4.
Nakagawa K, Chen R, Ross G, Donlon T, Allsopp R, Willcox D, et al.
J Hypertens
. 2023 Nov;
42(3):484-489.
PMID: 38009316
Objective: The G -allele of FOXO3 SNP rs2802292 , which is associated with human resilience and longevity, has been shown to attenuate the impact of hypertension on the risk of...
5.
Morris B, Donlon T
Am J Hypertens
. 2023 Aug;
36(12):631-640.
PMID: 37561089
Background: Genetic factors influence lifespan. In humans, there appears to be a particularly strong genetic effect in those aged ≥ 90 years. An important contribution is nutrient sensing genes which...
6.
Chen R, Morris B, Donlon T, Ross G, Kallianpur K, Allsopp R, et al.
J Alzheimers Dis
. 2023 Jul;
95(1):79-91.
PMID: 37483002
Background: It is well established that mid-life hypertension increases risk of dementia, whereas the association of late-life hypertension with dementia is unclear. Objective: To determine whether FOXO3 longevity-associated genotype influences...
7.
Morris B, Chen R, Donlon T, Kallianpur K, Masaki K, Willcox B
Aging (Albany NY)
. 2023 May;
15(10):3967-3983.
PMID: 37178326
Longevity is written into the genes. While many so-called "longevity genes" have been identified, the reason why particular genetic variants are associated with longer lifespan has proven to be elusive....
8.
Donlon T, Morris B, Chen R, Lim E, Morgen E, Fortney K, et al.
Geroscience
. 2023 Mar;
45(4):2303-2324.
PMID: 36881352
FOXO3 is a ubiquitous transcription factor expressed in response to cellular stress caused by nutrient deprivation, inflammatory cytokines, reactive oxygen species, radiation, hypoxia, and other factors. We showed previously that...
9.
Orea-Soufi A, Paik J, Braganca J, Donlon T, Willcox B, Link W
Trends Pharmacol Sci
. 2022 Oct;
43(12):1070-1084.
PMID: 36280450
Forkhead box (FOX)O proteins are transcription factors (TFs) with four members in mammals designated FOXO1, FOXO3, FOXO4, and FOXO6. FOXO TFs play a pivotal role in the cellular adaptation to...
10.
Donlon T, Morris B, Masaki K, Chen R, Davy P, Kallianpur K, et al.
J Gerontol A Biol Sci Med Sci
. 2022 Aug;
77(8):1479-1484.
PMID: 35960854
No abstract available.