Bradley J Willcox
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Explore the profile of Bradley J Willcox including associated specialties, affiliations and a list of published articles.
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107
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3782
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Recent Articles
1.
Association of alcohol with lung cancer risk in men with different growth hormone receptor genotypes
Chen R, Donlon T, Morris B, Allsopp R, Willcox B, Masaki K
Lung Cancer
. 2024 Nov;
198:107971.
PMID: 39541775
Objective: To test whether genetic variants of the growth hormone receptor gene (GHR) modulate the effect of lifestyle variables on lung cancer (LC) risk. Materials And Methods: This population-based cohort...
2.
Chen R, Morris B, Donlon T, Nakagawa K, Allsopp R, Willcox B, et al.
J Gerontol A Biol Sci Med Sci
. 2024 Nov;
79(12).
PMID: 39497655
Background: This study tested whether the carriage of the longevity-associated G-allele of FOXO3 SNP rs2802292 (TG/GG) protects against incident coronary artery disease (CAD) in men with hypertension. Methods: Subjects were...
3.
Li M, Fujiyoshi A, Willcox B, Willcox B, Li J, Kadota A, et al.
Eur Heart J Cardiovasc Imaging
. 2024 Oct;
26(2):273-279.
PMID: 39437331
Aims: Continued low mortality from coronary heart disease in Japan, despite deleterious changes in traditional risk factors, remains unexplained. Since aortic calcification (AC) was an early predictor of cardiovascular mortality,...
4.
Olshansky S, Willcox B, Demetrius L, Beltran-Sanchez H
Nat Aging
. 2024 Oct;
4(11):1635-1642.
PMID: 39375565
Over the course of the twentieth century, human life expectancy at birth rose in high-income nations by approximately 30 years, largely driven by advances in public health and medicine. Mortality...
5.
Noureddine S, Schneider A, Strader S, Zhu X, Dhahbi J, Allsopp R, et al.
Aging Cell
. 2024 May;
23(8):e14191.
PMID: 38751007
Nonagenarians and centenarians serve as successful examples of aging and extended longevity, showcasing robust regulation of biological mechanisms and homeostasis. Given that human longevity is a complex field of study...
6.
Novel protective effect of the FOXO3 longevity genotype on mechanisms of cellular aging in Okinawans
Torigoe T, Willcox D, Shimabukuro M, Higa M, Gerschenson M, Andrukhiv A, et al.
NPJ Aging
. 2024 Mar;
10(1):18.
PMID: 38459055
The genetic association of FOXO3 genotypes with human longevity is well established, although the mechanism is not fully understood. We now report on the relationship of the FOXO3 longevity variant...
7.
Medoro A, Davinelli S, Milella L, Willcox B, Allsopp R, Scapagnini G, et al.
Mar Drugs
. 2023 Dec;
21(12).
PMID: 38132964
Decreased adult neurogenesis, or the gradual depletion of neural stem cells in adult neurogenic niches, is considered a hallmark of brain aging. This review provides a comprehensive overview of the...
8.
Harrison D, Strong R, Reifsnyder P, Rosenthal N, Korstanje R, Fernandez E, et al.
Geroscience
. 2023 Dec;
46(1):795-816.
PMID: 38041783
In genetically heterogeneous (UM-HET3) mice produced by the CByB6F1 × C3D2F1 cross, the Nrf2 activator astaxanthin (Asta) extended the median male lifespan by 12% (p = 0.003, log-rank test), while...
9.
Nakagawa K, Chen R, Ross G, Donlon T, Allsopp R, Willcox D, et al.
J Hypertens
. 2023 Nov;
42(3):484-489.
PMID: 38009316
Objective: The G -allele of FOXO3 SNP rs2802292 , which is associated with human resilience and longevity, has been shown to attenuate the impact of hypertension on the risk of...
10.
Chen R, Morris B, Donlon T, Ross G, Kallianpur K, Allsopp R, et al.
J Alzheimers Dis
. 2023 Jul;
95(1):79-91.
PMID: 37483002
Background: It is well established that mid-life hypertension increases risk of dementia, whereas the association of late-life hypertension with dementia is unclear. Objective: To determine whether FOXO3 longevity-associated genotype influences...