Timofey V Tselykh
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Explore the profile of Timofey V Tselykh including associated specialties, affiliations and a list of published articles.
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8
Citations
317
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Recent Articles
1.
Kalendar R, Tselykh T, Khassenov B, Ramanculov E
Methods Mol Biol
. 2017 May;
1620:33-64.
PMID: 28540698
This chapter introduces the FastPCR software as an integrated tool environment for PCR primer and probe design, which predicts properties of oligonucleotides based on experimental studies of the PCR efficiency....
2.
Makela J, Tselykh T, Kukkonen J, Eriksson O, Korhonen L, Lindholm D
Neuropharmacology
. 2015 Dec;
102:266-75.
PMID: 26631533
Mitochondrial dysfunction has been linked to several neurodegenerative diseases such as Parkinson's disease (PD). Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a master gene for mitochondrial biogenesis and has been shown...
3.
Makela J, Tselykh T, Maiorana F, Eriksson O, Do H, Mudo G, et al.
Springerplus
. 2015 May;
3:2.
PMID: 25932355
Mitochondrial dysfunctions accompany several neurodegenerative disorders and contribute to disease pathogenesis among others in Parkinson's disease (PD). Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is a major regulator of mitochondrial functions...
4.
Do H, Tselykh T, Makela J, Ho T, Olkkonen V, Bornhauser B, et al.
J Biol Chem
. 2012 Mar;
287(16):12602-11.
PMID: 22378787
The LDLR is a critical factor in the regulation of blood cholesterol levels that are altered in different human diseases. The level of LDLR in the cell is regulated by...
5.
Mudo G, Makela J, Di Liberto V, Tselykh T, Olivieri M, Piepponen P, et al.
Cell Mol Life Sci
. 2011 Oct;
69(7):1153-65.
PMID: 21984601
Mitochondrial dysfunction and oxidative stress occur in Parkinson's disease (PD), but little is known about the molecular mechanisms controlling these events. Peroxisome proliferator-activated receptor-gamma coactivator-1α (PGC-1α) is a transcriptional coactivator...
6.
Helenius K, Yang Y, Tselykh T, Pessa H, Frilander M, Makela T
Nucleic Acids Res
. 2011 Mar;
39(12):5025-35.
PMID: 21385826
The relevance of serine 5 phosphorylation of RNA polymerase II carboxy-terminal domain during initiation has been difficult to determine in mammalian cells as no general in vivo Ser5 kinase has...
7.
Ivanov K, Tselykh T, Heino T, Makinen K
J RNAi Gene Silencing
. 2009 Sep;
1(1):12-20.
PMID: 19771199
RNA interference (RNAi) is mediated by a multicomponent RNA-induced silencing complex (RISC). Here we examine the phosphorylation state of three Drosophila RISC-associated proteins, VIG, R2D2 and a truncated form of...
8.
Tselykh T, Roos C, Heino T
Exp Cell Res
. 2005 May;
307(2):354-66.
PMID: 15894314
We report on the essential Drosophila mRpL55 gene conserved exclusively in metazoans. Null mRpL55 mutants did not grow after hatching, moved slowly and died as first instar larvae. MrpL55 is...