Tilman Sanchez-Elsner
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Explore the profile of Tilman Sanchez-Elsner including associated specialties, affiliations and a list of published articles.
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49
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2123
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Recent Articles
1.
Li Y, Ramirez-Suastegui C, Harris R, Castaneda-Castro F, Ascui G, Perez-Jeldres T, et al.
Nat Immunol
. 2024 Jun;
25(7):1231-1244.
PMID: 38898157
To understand the role of T cells in the pathogenesis of ulcerative colitis (UC), we analyzed colonic T cells isolated from patients with UC and controls. Here we identified colonic...
2.
Kyyaly M, Vorobeva E, Kothalawala D, Fong W, He P, Sones C, et al.
J Pers Med
. 2022 Apr;
12(4).
PMID: 35455659
Micro RNAs (miRNAs) are short, non-coding RNAs (Ribonucleic acids) with regulatory functions that could prove useful as biomarkers for asthma diagnosis and asthma severity-risk stratification. The objective of this systematic...
3.
McCann K, von Witzleben A, Thomas J, Wang C, Wood O, Singh D, et al.
J Immunother Cancer
. 2022 Apr;
10(3).
PMID: 35361728
Background: Cancer is characterized by an accumulation of somatic mutations, of which a significant subset can generate cancer-specific neoepitopes that are recognized by autologous T cells. Such neoepitopes are emerging...
4.
Eschweiler S, Clarke J, Ramirez-Suastegui C, Panwar B, Madrigal A, Chee S, et al.
Nat Immunol
. 2021 Jun;
22(8):1052-1063.
PMID: 34168370
Immune-checkpoint blockade (ICB) has shown remarkable clinical success in boosting antitumor immunity. However, the breadth of its cellular targets and specific mode of action remain elusive. We find that tumor-infiltrating...
5.
Kyyaly M, Sanchez-Elsner T, He P, Sones C, Arshad S, Kurukulaaratchy R
Clin Transl Allergy
. 2021 Jun;
11(4):e12040.
PMID: 34161666
Background: Identifying patients at risk of severe asthma is vitally important given the disproportionate burden of disease imposed by that state. However, biomarkers to support such needs remain elusive. Methods:...
6.
Dharmasiri S, Garrido-Martin E, Harris R, Bateman A, Collins J, Cummings J, et al.
Inflamm Bowel Dis
. 2021 Feb;
27(10):1641-1652.
PMID: 33570153
Background: Intestinal macrophages are key immune cells in the maintenance of intestinal immune homeostasis and have a role in the pathogenesis of inflammatory bowel disease (IBD). However, the mechanisms by...
7.
Garrido-Martin E, Mellows T, Clarke J, Ganesan A, Wood O, Cazaly A, et al.
J Immunother Cancer
. 2020 Jul;
8(2).
PMID: 32699181
Background: The role of tumor-associated macrophages (TAMs) in determining the outcome between the antitumor effects of the adaptive immune system and the tumor's anti-immunity stratagems, is controversial. Macrophages modulate their...
8.
de Abajo F, Hernandez R, Kaminer I, Meyerhans A, Rosell-Llompart J, Sanchez-Elsner T
ACS Nano
. 2020 Jun;
14(7):7704-7713.
PMID: 32551537
We advocate the widespread use of UV-C light as a short-term, easily deployable, and affordable way to limit virus spread in the current SARS-CoV-2 pandemic. Radical social distancing with the...
9.
Francisco-Garcia A, Garrido-Martin E, Rupani H, Lau L, Martinez-Nunez R, Howarth P, et al.
Noncoding RNA
. 2019 Nov;
5(4).
PMID: 31684064
MicroRNAs are known to regulate important pathways in asthma pathology including the IL-6 and IFN pathways. MicroRNAs have been found not only within cells but also within extracellular vesicles such...
10.
Felwick R, Dingley G, Martinez-Nunez R, Sanchez-Elsner T, Cummings J, Collins J
J Crohns Colitis
. 2019 Oct;
14(3):381-392.
PMID: 31626694
Background And Aims: Mucosal healing is important in Crohn's disease therapies. Epithelial homeostasis becomes dysregulated in Crohn's, with increased permeability, inflammation, and diarrhoea. MicroRNAs are small non-coding RNAs that regulate...