Tianxu Han
Overview
Explore the profile of Tianxu Han including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
277
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Recent Articles
1.
Guan M, Lim L, Holguin L, Han T, Vyas V, Urak R, et al.
Mol Ther Methods Clin Dev
. 2022 May;
25:344-359.
PMID: 35573050
T cells engineered to express HIV-specific chimeric antigen receptors (CARs) represent a promising strategy to clear HIV-infected cells, but to date have not achieved clinical benefits. A likely hurdle is...
2.
Wang X, Urak R, Walter M, Guan M, Han T, Vyas V, et al.
J Immunother Cancer
. 2022 Jan;
10(1).
PMID: 35027426
Background: Adoptive transfer of CD19-specific chimeric antigen receptor (CD19CAR) T cells can induce dramatic disease regression in patients with B cell malignancies. CD19CAR T cell therapy may be limited by...
3.
Liu C, Han T, Stachura D, Wang H, Vaisman B, Kim J, et al.
Nat Commun
. 2018 Apr;
9(1):1310.
PMID: 29615667
Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for hematopoietic stem progenitor cell...
4.
Han T, Yang C, Chang K, Zhang D, Imam F, Rana T
EMBO Rep
. 2016 Nov;
17(12):1814-1828.
PMID: 27797851
Hematopoietic stem cells (HSCs) are capable of giving rise to all blood cell lineages throughout adulthood, and the generation of engraftable HSCs from human pluripotent stem cells is a major...
5.
Johnson T, Chin M, Han T, Shen J, Rana T, Siegel D
J Am Chem Soc
. 2016 Apr;
138(18):6068-73.
PMID: 27096704
Improving the ex vivo and in vivo production of hematopoietic stem and progenitor cells (HSPCs) has the potential to address the short supply of these cells that are used in...
6.
Lin N, Chang K, Li Z, Gates K, Rana Z, Dang J, et al.
Mol Cell
. 2014 Feb;
53(6):1005-19.
PMID: 24530304
Here, we generated a genome-scale shRNA library targeting long intergenic noncoding RNAs (lincRNAs) in the mouse. We performed an unbiased loss-of-function study in mouse embryonic stem cells (mESCs) and identified...