Thornton W Thompson
Overview
Explore the profile of Thornton W Thompson including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
1034
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tenthorey J, Chavez R, Thompson T, Deets K, Vance R, Rauch I
J Exp Med
. 2020 Apr;
217(7).
PMID: 32342103
The NAIP/NLRC4 inflammasome is a cytosolic sensor of bacteria that activates caspase-1 and initiates potent immune responses. Structural, biochemical, and genetic data demonstrate that NAIP proteins are receptors for bacterial...
2.
Hsu J, Hodgins J, Marathe M, Nicolai C, Bourgeois-Daigneault M, Trevino T, et al.
J Clin Invest
. 2018 Sep;
128(10):4654-4668.
PMID: 30198904
Checkpoint blockade immunotherapy targeting the PD-1/PD-L1 inhibitory axis has produced remarkable results in the treatment of several types of cancer. Whereas cytotoxic T cells are known to provide important antitumor...
3.
Thompson T, Jackson B, Li P, Wang J, Kim A, Huang K, et al.
Elife
. 2018 May;
7.
PMID: 29757143
NKG2D is an important immunoreceptor expressed on the surface of NK cells and some T cells. NKG2D recognizes a set of ligands typically expressed on infected or transformed cells, but...
4.
Mostafa H, Thompson T, Konen A, Haenchen S, Hilliard J, Macdonald S, et al.
J Virol
. 2018 Jan;
92(7).
PMID: 29321311
In the process of generating herpes simplex virus 1 (HSV-1) mutations in the viral regulatory gene encoding infected cell protein 0 (ICP0), we isolated a viral mutant, termed KOS-NA, that...
5.
Thompson T, Kim A, Li P, Wang J, Jackson B, Huang K, et al.
Elife
. 2017 Dec;
6.
PMID: 29231815
Natural Killer (NK) cells confer protection from tumors and infections by releasing cytotoxic granules and pro-inflammatory cytokines upon recognition of diseased cells. The responsiveness of NK cells to acute stimulation...
6.
Iannello A, Thompson T, Ardolino M, Marcus A, Raulet D
Curr Opin Immunol
. 2015 Dec;
38:52-8.
PMID: 26686774
Increasing evidence supports a role for innate immune effector cells in tumor surveillance. Natural killer (NK) cells and myeloid cells represent the two main subsets of innate immune cells possessing...
7.
Marcus A, Gowen B, Thompson T, Iannello A, Ardolino M, Deng W, et al.
Adv Immunol
. 2014 Feb;
122:91-128.
PMID: 24507156
In recent years, roles of the immune system in immune surveillance of cancer have been explored using a variety of approaches. The roles of the adaptive immune system have been...
8.
Iannello A, Thompson T, Ardolino M, Lowe S, Raulet D
J Exp Med
. 2013 Sep;
210(10):2057-69.
PMID: 24043758
The induction of cellular senescence is an important mechanism by which p53 suppresses tumorigenesis. Using a mouse model of liver carcinoma, where cellular senescence is triggered in vivo by inducible...
9.
Mostafa H, Thompson T, Davido D
J Virol
. 2012 Dec;
87(4):2109-19.
PMID: 23221554
The herpes simplex virus 1 (HSV-1) infected cell protein 0 (ICP0) is an immediate-early phosphoprotein that transactivates viral gene expression. Evidence suggests that phosphorylation regulates the functions of ICP0, and...
10.
Mostafa H, Thompson T, Kushnir A, Haenchen S, Bayless A, Hilliard J, et al.
J Virol
. 2011 Sep;
85(23):12631-7.
PMID: 21937654
In cell culture experiments, phosphorylation appears to be a critical regulator of the herpes simplex virus 1 (HSV-1) immediate-early (IE) protein, ICP0, which is an E3 ubiquitin ligase that transactivates...